Evidence map›Paper›PMID 39324804›Full record

ArticleJournal of public health (Oxford, England)2025

Cardiovascular presentations during the COVID-19 pandemic: an interrupted time series analysis.

Hari Prakash Sritharan, Harrison Nguyen, Usaid Khalil Allahwala, Ravinay Bhindi

Abstract readMulticenter Study
In one paragraph

Article in Journal of public health (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Hari Prakash SritharanFaculty of Medicine and Health, University of Sydney, Science Road, Camperdown, Sydney, NSW 2050, Australia.ORCID 0000-0001-7352-900X
Harrison NguyenRoyal North Shore Hospital, Reserve Road, St Leonards, Sydney, NSW 2065, Australia.
Usaid Khalil AllahwalaFaculty of Medicine and Health, University of Sydney, Science Road, Camperdown, Sydney, NSW 2050, Australia.
Ravinay BhindiFaculty of Medicine and Health, University of Sydney, Science Road, Camperdown, Sydney, NSW 2050, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe broader implications of the Coronavirus disease 2019 pandemic on cardiovascular hospitalizations remain unclear. We aimed to assess trends in cardiovascular presentations during the Coronavirus disease 2019 pandemic.

methodsThis multicentre study examined cardiovascular presentations from March 2018 to February 2023. Patients with cardiovascular presentations were identified through administrative health records using ICD-10-AM diagnosis codes. Four key study periods were analysed: T0-pre-pandemic, T1-first lockdown, T2-easing of restrictions and T3-release of restrictions and widespread vaccination. Interrupted time series analysis was used to predict weekly cardiovascular presentations, with the mean difference between actual and predicted numbers assessed for significance.

resultsOverall, 116 518 patients were included across three major public hospitals in Australia. Cardiovascular presentations were significantly lower in T1 than predicted, with a mean decline of 13.1% (SD 16.2%; P = 0.004). There was a significant difference between the expected and actual number of most cardiovascular presentations in T2 and T3, apart from a significant reduction in cardiomyopathy and heart failure presentations during T3 (4.5% [SD 23.7%]; P = 0.007).

conclusionsCardiovascular presentations were significantly lower during the initial lockdown phase of the COVID-19 pandemic; this attenuated with easing of social restrictions and widespread vaccination, except for persistent reduction in cardiomyopathy and heart failure presentations.

Indexed as

Cardiovascular DiseasesCOVID-19AdultAgedAustraliaFemaleHospitalizationHumansInterrupted Time Series AnalysisMaleMiddle AgedPandemicsSARS-CoV-2cardiomyopathycardiovascular diseaseCovid-19heart failure

Identifiers

PMID39324804
PMCPMC11879051

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.