Evidence map›Paper›PMID 39324799›Full record

ArticleAntimicrobial agents and chemotherapy2024

An arylsulfonamide that targets cell wall biosynthesis in

Renee Allen, Lauren Ames, Vanessa Pietrowski Baldin, Arielle Butts, Kenneth J Henry, Greg Durst, Diana Quach, Joseph Sugie, Joe Pogliano, Tanya Parish

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Thienopyrimidine amide analogs target MmpL3 inAntimicrobial agents and chemotherapy · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Renee AllenCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Lauren AmesCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Vanessa Pietrowski BaldinCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Arielle ButtsCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Kenneth J HenryLgenia, Fortville, Indiana, USA.
Greg DurstLgenia, Fortville, Indiana, USA.
Diana QuachLinnaeus Bioscience Inc., San Diego, California, USA.
Joseph SugieLinnaeus Bioscience Inc., San Diego, California, USA.
Joe PoglianoLinnaeus Bioscience Inc., San Diego, California, USA.
Tanya ParishCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.ORCID 0000-0001-7507-0423

Funding

Bill and Melinda Gates Foundation (GF) INV-005585,INV-056399
6 · The paper itself

Abstract

We investigated the mechanism of action of an arylsulfonamide with whole-cell activity against

Indexed as

Antitubercular AgentsBacterial ProteinsCell WallMicrobial Sensitivity TestsMycobacterium tuberculosisSulfonamidesHep G2 CellsHumansMembrane Transport ProteinsMycolic AcidsReactive Oxygen SpeciesAntitubercular AgentsBacterial ProteinsMembrane Transport ProteinsMmpL3 protein, Mycobacterium tuberculosisMycolic AcidsReactive Oxygen SpeciesSulfonamidesantitubercularcell wallMmpL3mode of actionmycobacteriatuberculosis

Identifiers

PMID39324799
PMCPMC11539219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.