Evidence map›Paper›PMID 39324734›Full record

ReviewTherapeutic delivery2024

Exploring delivery systems for targeted nanotechnology-based gene therapy in the inner ear.

Thomas Foster, Patrick Lim, Corina Mihaela Ionescu, Susbin Raj Wagle, Bozica Kovacevic, Armin Mooranian, Hani Al-Salami

Abstract readReview
In one paragraph

Review in Therapeutic delivery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thomas FosterThe Biotechnology & Drug Development Research Laboratory, Curtin Medical School & Curtin Health Innovation Research Institute, Curtin University, Bentley, 6102, Western Australia, Australia.ORCID 0000-0003-1779-0785
Patrick LimThe Biotechnology & Drug Development Research Laboratory, Curtin Medical School & Curtin Health Innovation Research Institute, Curtin University, Bentley, 6102, Western Australia, Australia.ORCID 0009-0008-1073-8101
Corina Mihaela IonescuThe Biotechnology & Drug Development Research Laboratory, Curtin Medical School & Curtin Health Innovation Research Institute, Curtin University, Bentley, 6102, Western Australia, Australia.ORCID 0000-0002-8966-0448
Susbin Raj WagleThe Biotechnology & Drug Development Research Laboratory, Curtin Medical School & Curtin Health Innovation Research Institute, Curtin University, Bentley, 6102, Western Australia, Australia.ORCID 0000-0001-9867-8896
Bozica KovacevicThe Biotechnology & Drug Development Research Laboratory, Curtin Medical School & Curtin Health Innovation Research Institute, Curtin University, Bentley, 6102, Western Australia, Australia.ORCID 0000-0002-9359-7840
Armin MooranianThe Biotechnology & Drug Development Research Laboratory, Curtin Medical School & Curtin Health Innovation Research Institute, Curtin University, Bentley, 6102, Western Australia, Australia.ORCID 0000-0001-7103-2067
Hani Al-SalamiThe Biotechnology & Drug Development Research Laboratory, Curtin Medical School & Curtin Health Innovation Research Institute, Curtin University, Bentley, 6102, Western Australia, Australia.ORCID 0000-0003-0049-6969

Funding

Curtin University (Perth, Western Australia) Internal Funding APP9000597National Health Medical Research Council Medical Research Future Fund (NHMRC-MRFF) MRF2017281West Australian Department of Health's Future Health Innovation Research Fund IF2022-23/4
6 · The paper itself

Abstract

Hearing loss places a significant burden on our aging population. However, there has only been limited progress in developing therapeutic techniques to effectively mediate this condition. This review will outline several of the most commonly utilized practices for the treatment of sensorineural hearing loss before exploring more novel techniques currently being investigated via both

Indexed as

Ear, InnerGenetic TherapyGene Transfer TechniquesAnimalsGenetic VectorsHearing Loss, SensorineuralHumansNanotechnologybile acidsgene deliveryhearing lossnanotechnologystem cells

Identifiers

PMID39324734
PMCPMC11457609

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.