Evidence map›Paper›PMID 39324420›Full record

ArticleBiopharmaceutics & drug disposition2024

A limited sampling model to estimate the area under the curve of mycophenolic acid in hematopoietic stem cell transplantation recipients.

Liangmo Lin, Mianhui Hong, Xiangjun Fu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biopharmaceutics & drug disposition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Liangmo LinPharmacy Department, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.ORCID https://orcid.org/0000-0002-0988-2228
Mianhui HongPharmacy Department, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.
Xiangjun FuHematological Department, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.ORCID https://orcid.org/0009-0000-9304-2573

Funding

Hainan Provincial Natural Science Foundation of China 822QN452
6 · The paper itself

Abstract

Relationship between the areas under the curve (AUC) of mycophenolic acid (MPA) and the likelihood of rejection is well-established in solid organ transplantation recipients. In hematopoietic stem cell transplantation (HSCT), MPA AUC is also linked to graft versus host disease. This study aimed to develop a simplified method to estimate MPA AUC

Indexed as

Area Under CurveHematopoietic Stem Cell TransplantationImmunosuppressive AgentsMycophenolic AcidAdolescentAdultFemaleHumansMaleMiddle AgedModels, BiologicalYoung AdultImmunosuppressive AgentsMycophenolic Acidallogeneic hematopoietic stem cell transplantationlimited sampling modelMPA AUC0–12mycophenolate mofetilmycophenolic acid

Identifiers

PMID39324420
PMCPMC11687408

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.