Evidence map›Paper›PMID 39324056›Full record

ArticleFrontiers in cellular and infection microbiology2024

Genetic landscape of ESBL producing international clone ST410 of

Sandip Patil, Liu Pai, Hongyu Chen, Yunsheng Chen, Li Xinye, Shaowei Dong, Sanket Kaushik, Bruno Silvester Lopes, Xiaowen Chen, Sixi Liu and 1 more

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Novel Variant of New Delhi Metallo-Beta-Lactamase (Antibiotics (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sandip PatilDepartment of Haematology and Oncology, Shenzhen Children's Hospital, Shenzhen, China.
Liu PaiPaediatric Research Institute, Shenzhen Children's Hospital, Shenzhen, China.
Hongyu ChenDepartment of Laboratory Medicine, Shenzhen Children's Hospital, Shenzhen, China.
Yunsheng ChenDepartment of Laboratory Medicine, Shenzhen Children's Hospital, Shenzhen, China.
Li XinyeDepartment of Paediatric, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Shaowei DongDepartment of Haematology and Oncology, Shenzhen Children's Hospital, Shenzhen, China.
Sanket KaushikDepartment of Biotechnology, Amity University, Jaipur, India.
Bruno Silvester LopesSchool of Health and Life Sciences, Teesside University, Middlesbrough, United Kingdom.
Xiaowen ChenDepartment of Haematology and Oncology, Shenzhen Children's Hospital, Shenzhen, China.
Sixi Liu *Department of Haematology and Oncology, Shenzhen Children's Hospital, Shenzhen, China.
Feiqiu Wen *Department of Haematology and Oncology, Shenzhen Children's Hospital, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The emergence of ESBLs producing cephalosporin-resistant Methods: 29 Results: Antimicrobial susceptibility testing demonstrated a high level of resistance to cephalosporins followed by aminoglycoside, sulfonamide, carbapenem and penicillin group of antibiotics. However, n=20/29 shows MDR phenotype. Phylogenetic group B2 (n=15) dominated, followed by group D (n=7), group A (n=4), and group B1 (n=3). Serotyping analysis identified O1:H7 (n=8), O2:H1 (n=6), O8:H4 (n=5), O16:H5 (n=4), and O25:H4 (n=3). Other serotypes identified included O6:H1, O15:H5, and O18:H7 (n=1 each). The most commonly detected ESBL genes were Conclusion: The ST410 clone exhibited a complex resistance profile, diverse serotypes, the presence of specific resistance genes (ESBL genes), virulence gene repertoire, and diverse plasmids. The

Indexed as

Anti-Bacterial Agentsbeta-LactamasesEscherichia coliEscherichia coli InfectionsMicrobial Sensitivity TestsMultilocus Sequence TypingPhylogenyPlasmidsVirulence FactorsWhole Genome SequencingChildChild, PreschoolChinaDrug Resistance, Multiple, BacterialFemaleGenotypeAnti-Bacterial Agentsbeta-LactamasesVirulence Factorsantimicrobial susceptibilitycephalosporin resistanceE. coliESBLinternational high-risk clone ST410pediatric patientsWGS

Identifiers

PMID39324056
PMCPMC11422233

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.