Evidence map›Paper›PMID 39323910›Full record

ReviewFrontiers in surgery2024

Surgical management of anastomotic leakage related to ovarian cancer surgery: a narrative review.

Stefano Restaino, Sofia Schierano, Martina Arcieri, Barbara Costantini, Alice Poli, Sara Pregnolato, Giovanni Terrosu, Sergio Calandra, Marco Petrillo, Giulia Pellecchia and 10 more

Abstract readReview
In one paragraph

Review in Frontiers in surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Stefano RestainoDepartment of Medical Area (DMED), Clinic of Obstetrics and Gynecology Unit, Santa Maria Della Misericordia Hospital, Azienda Sanitaria Friuli Centrale, Udine, Italy.
Sofia SchieranoDepartment of Medical Area (DMED), Clinic of Obstetrics and Gynecology Unit, Santa Maria Della Misericordia Hospital, Azienda Sanitaria Friuli Centrale, Udine, Italy.
Martina ArcieriDepartment of Medical Area (DMED), Clinic of Obstetrics and Gynecology Unit, Santa Maria Della Misericordia Hospital, Azienda Sanitaria Friuli Centrale, Udine, Italy.
Barbara CostantiniDipartimento per le Scienze Della Salute Della Donna, del Bambino e di Sanità Pubblic, Unit of Gynecologic Oncology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Alice PoliDepartment of Medical Area (DMED), Clinic of Obstetrics and Gynecology Unit, Santa Maria Della Misericordia Hospital, Azienda Sanitaria Friuli Centrale, Udine, Italy.
Sara PregnolatoDepartment of Medical Area (DMED), Clinic of Obstetrics and Gynecology Unit, Santa Maria Della Misericordia Hospital, Azienda Sanitaria Friuli Centrale, Udine, Italy.
Giovanni TerrosuLiver-Kidney Transplant Unit, Department of Medical Area (DMED), Santa Maria Della Misericordia Hospital, Azienda Sanitaria Friuli Centrale, Udine, Italy.
Sergio CalandraLiver-Kidney Transplant Unit, Department of Medical Area (DMED), Santa Maria Della Misericordia Hospital, Azienda Sanitaria Friuli Centrale, Udine, Italy.
Marco PetrilloGynecologic and Obstetric Clinic, Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy.
Giulia PellecchiaDepartment of Medical Area (DMED), Clinic of Obstetrics and Gynecology Unit, Santa Maria Della Misericordia Hospital, Azienda Sanitaria Friuli Centrale, Udine, Italy.
Alessandro LucidiCentre for Fetal Care and High-Risk Pregnancy, Department of Obstetrics and Gynecology, University of Chieti, Chieti, Italy.
Marko KlarićDepartment of Obstetrics and Gynaecology, Clinical Hospital Center of Rijeka, Rijeka, Croatia.
Lorenza DriulDepartment of Medical Area (DMED), Clinic of Obstetrics and Gynecology Unit, Santa Maria Della Misericordia Hospital, Azienda Sanitaria Friuli Centrale, Udine, Italy.
Vito ChianteraDepartment of Health Promotion, Mother and Childcare, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy.
Alfredo ErcoliUnit of Gynecology and Obstetrics, Department of Human Pathology of Adults and Childhood, University Hospital "G.Martino", Messina, Italy.
Cristina TalientoDepartment of Obstetrics and Gynecology, University Hospital Ferrara, Ferrara, Italy.
Francesco FanfaniDipartimento per le Scienze Della Salute Della Donna, del Bambino e di Sanità Pubblic, Unit of Gynecologic Oncology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Anna FagottiDipartimento per le Scienze Della Salute Della Donna, del Bambino e di Sanità Pubblic, Unit of Gynecologic Oncology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Giovanni ScambiaDipartimento per le Scienze Della Salute Della Donna, del Bambino e di Sanità Pubblic, Unit of Gynecologic Oncology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Giuseppe VizzielliDepartment of Medical Area (DMED), Clinic of Obstetrics and Gynecology Unit, Santa Maria Della Misericordia Hospital, Azienda Sanitaria Friuli Centrale, Udine, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This narrative review describes the state of the art in the management of anastomotic leakage in ovarian cancer. Multiple surgical procedures, including bowel resection, are often required to achieve "optimal" cytoreduction in locally advanced ovarian cancer. Intestinal anastomosis is currently the most common way to restore bowel continuity. However, in some patients, a temporary protective stoma is indicated to prevent anastomotic leakage. This is an important issue to improve surgical outcomes and until recently there has been a lack of objective data to clarify the risk factors for anastomotic leakage. This review describes the risk factors for AL associated with surgery and compares the results of recent studies. We also review the current indications for placement of a protective ileostomy and treatment options for conservative management of AL. We present two examples of practical clinical AL risk calculators, in addition to the most assessed AL risk factor. To date, the decision-making processes that lead surgeons to perform a protective ileostomy are quite heterogeneous and based on the personal experience of the surgeon, mainly depending on individual training. Three different management options after colorectal anastomosis in OC are described: conservative management, diversion ileostomy and ghost ileostomy.

Indexed as

anastomosis leakagedebulking surgeryovarian cancerrectosigmoid resectionrisk factorsstoma

Identifiers

PMID39323910
PMCPMC11422216

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.