Evidence map›Paper›PMID 39323906›Full record

ArticlePhysical review applied2023

Laboratory-based x-ray dark-field microscopy.

Michela Esposito, Ian Buchanan, Lorenzo Massimi, Joseph D Ferrara, Paul R Shearing, Alessandro Olivo, Marco Endrizzi

Abstract read
In one paragraph

Article in Physical review applied, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michela EspositoDepartment of Medical Physics and Biomedical Engineering, University College London, Malet Place, Gower Street, London WC1E 6BT, United Kingdom.
Ian BuchananDepartment of Medical Physics and Biomedical Engineering, University College London, Malet Place, Gower Street, London WC1E 6BT, United Kingdom.
Lorenzo MassimiDepartment of Medical Physics and Biomedical Engineering, University College London, Malet Place, Gower Street, London WC1E 6BT, United Kingdom.
Joseph D FerraraRigaku Americas Corporation, 9009 New Trails Drive, The Woodlands, Texas 77381, US.
Paul R ShearingDepartment of Chemical Engineering, Electrochemical Innovation Lab, University College London, London WC1E 7JE, UK.
Alessandro OlivoDepartment of Medical Physics and Biomedical Engineering, University College London, Malet Place, Gower Street, London WC1E 6BT, United Kingdom.
Marco EndrizziDepartment of Medical Physics and Biomedical Engineering, University College London, Malet Place, Gower Street, London WC1E 6BT, United Kingdom.

Funding

A soft X-Ray Phase-Based Microscope for Biomedical ApplicationsR01EB028829 · NIBIB · RIGAKU AMERICAS CORPORATION · PI FERRARA, JOSEPH DAVID, MAKAROVA, OLGA V. · 2020 to 2023
$2.1M
NIBIB NIH HHS R01 EB028829Wellcome Trust
6 · The paper itself

Abstract

We demonstrate the capability of laboratory-based x-ray microscopes, using intensity-modulation masks, to access the sub-micron length scale in the dark field contrast channel while maintaining micron resolution in the resolved (refraction and attenuation) channels. The dark field contrast channel reveals the presence of ensembles of samples' features below the system resolution. Resolved refraction and attenuation channels provide multi-modal high-resolution imaging down to the micron scale. We investigate the regimes of modulated and un-modulated dark field as well as refraction, quantifying their dependence on the relationship between feature size in the imaged object and aperture size in the intensity-modulation mask. We propose an analytical model to link the measured signal with the sample's microscopic properties. Finally, we demonstrate the relevance of the microscopic dark field contrast channel in applications from both the life and physical sciences, providing proof of concept results for imaging collagen bundles in cartilage and dendritic growth in lithium batteries.

Identifiers

PMID39323906
PMCPMC11423780

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.