Evidence map›Paper›PMID 39323834›Full record

ArticleHeliyon2024

Blue light emitting graphene quantum dots/ Rhodamine B doped gold nanostars for ratiometric detection of methotrexate.

Masoud Gazizadeh, Masoumeh Foroutan Koudehi, Hossein Fasihi, Jafar Soleymani, Ramin Zibaseresht

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Masoud GazizadehToxicology Research Center, AJA University of Medical Sciences, Tehran, Iran.
Masoumeh Foroutan KoudehiBiomaterials and Medicinal Chemistry Research Center, AJA University of Medical Sciences, Tehran, Iran.
Hossein FasihiBiomaterials and Medicinal Chemistry Research Center, AJA University of Medical Sciences, Tehran, Iran.
Jafar SoleymaniPharmaceutical Analysis Research Center, Tabriz University of Medical Sciences, Iran.
Ramin ZibasereshtBiomaterials and Medicinal Chemistry Research Center, AJA University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, an innovative ratiometric sensing platform was developed for the determination of methotrexate (MTX), an antifolate drug, a chemotherapy agent, and an immune system suppressant based on blue emission graphene quantum dots/Rhodamine B doped gold nanostars (B-GQDs/Au NSt-RB). The developed sensor was a dual-emission fluorescent probe with two major emission peaks at 440 nm (B-GQDs) and 580 nm (Au NSt-RB) by exciting at 330 nm. Based on the inhibiting effect of MTX on the system's fluorescence density, the stable ratiometric fluorescent probe was used for the rapid determination of MTX in aquatic solutions and spiked human serum samples. The results indicated good linear correlations over the logarithmic concentration range of 0.3 nM-50.0 μM. In addition, B-GQDs/Au NSt-RB can further realize highly sensitive detection of MTX with a low LOD value of 2.28 × 10

Indexed as

AntifolateAu nanostarDual-emission fluorescent sensorGraphene quantum dotsMethotrexateQuenchingRatiometric fluorescence

Identifiers

PMID39323834
PMCPMC11422580

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.