Evidence map›Paper›PMID 39323745›Full record

ArticleRegenerative biomaterials2024

Recombinant collagen for the repair of skin wounds and photo-aging damage.

Taishan Liu, Jiayun Hao, Huan Lei, Yanru Chen, Lin Liu, Liping Jia, Juan Gu, Huaping Kang, Jingjing Shi, Jing He and 3 more

Erratum issuedAbstract read
In one paragraph

Article in Regenerative biomaterials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Seed Oil ofInternational journal of molecular sciences · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Taishan LiuShaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Xi'an 710069, China.
Jiayun HaoShaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Xi'an 710069, China.
Huan LeiShaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Xi'an 710069, China.
Yanru ChenShaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Xi'an 710069, China.
Lin LiuXi'an Giant Biotechnology Co. Ltd., Xi'an 710100, China.
Liping JiaXi'an Giant Biotechnology Co. Ltd., Xi'an 710100, China.
Juan GuShaanxi Giant Biotechnology Co. Ltd., Xi'an 710076, China.
Huaping KangShaanxi Giant Biotechnology Co. Ltd., Xi'an 710076, China.
Jingjing ShiShaanxi Giant Biotechnology Co. Ltd., Xi'an 710076, China.
Jing HeXi'an Giant Biotechnology Co. Ltd., Xi'an 710100, China.
Yangbin SongShaanxi Giant Biotechnology Co. Ltd., Xi'an 710076, China.
Yuqi TangShaanxi Giant Biotechnology Co. Ltd., Xi'an 710076, China.
Daidi FanShaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Xi'an 710069, China.ORCID https://orcid.org/0000-0001-9798-1674

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The skin, being the body's primary defense mechanism, is susceptible to various injuries such as epidermal wounds, natural aging, and ultraviolet-induced damage. As a result, there is growing interest in researching skin repair methods. Traditional animal-derived collagen, widely available on the market, poses risks due to its immunogenicity and potential for viral contamination. In contrast, recombinant collagen sourced from human genes offers a safer alternative. To investigate the potential of human recombinant collagen in skin repair, our research team applied two types, type I human collagen (Col I) and CF-1552(I), to two different skin injury models: a wound-healing model and a photo-aging model. Our findings indicate that both Col I and CF-1552(I) effectively enhance wound healing and repair skin damaged by ultraviolet exposure. Notably, CF-1552(I) showed effects comparable to Col I in promoting cell proliferation in the wound-healing model and increasing malondialdehyde content in the photo-aging model, suggesting that CF-1552(I) may offer greater potential for skin repair compared to the larger Col I molecule.

Indexed as

cell proliferationrecombinant collagenskin photo-aging repairwound repair

Identifiers

PMID39323745
PMCPMC11422187

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.