ArticleCureus2024
Unraveling the Relationship Between Vitamin D and Oxidative Stress: A Cross-Sectional Study.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Article
- Review
- Influence of Regular Breathing Exercises on Blood Pressure: A Cross-Sectional Study on Young Male Indian Population.Cureus · 2025Article
- Dietary Habits, Anthropometric Values, and Microvascular Reactivity in Older Persons of Both Sexes Living at Retirement Home in Osijek, Croatia.Clinical interventions in aging · 2025Observational
Corrections and comments
- Erratum issued
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionVitamin D, beyond bone metabolism, has played a significant role in various physiological processes, including modulation of oxidative stress and maintenance of vascular architecture. Oxidative stress, a state of altered balance between reactive oxygen species (ROS) and antioxidants, is a critical factor in the pathogenesis of various chronic diseases. Our study aims to explore the intricate relationship between serum vitamin D levels and markers of oxidative stress in normotensive and hypertensive individuals. MATERIALS AND
methodsA total of 108 age-matched participants (35 to 50 years) of both genders (54 males and 54 females) were included in this cross-sectional study according to the study design and assessed for their serum vitamin D level by using enzyme-linked immunosorbent assay (ELISA) method and serum malondialdehyde (MDA) level by using a spectrophotometer at 540 nm after measurement of the blood pressure. The data were entered in a Microsoft Excel sheet and analyzed using Statistical Package for Social Science (SPSS) software version 20.
resultsOur findings demonstrate a significant inverse correlation between serum vitamin D levels and MDA (r = -0.71, p < 0.001), indicating lower lipid peroxidation with higher vitamin D levels. Our study concludes by evident higher serum vitamin D levels associated with reduced oxidative stress, reflected by lower MDA.
conclusionThese findings suggest a potential protective role of vitamin D against oxidative damage, which could have implications for the prevention of oxidative stress-related diseases.
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