Evidence map›Paper›PMID 39323619›Full record

ArticleDEN open2025

Outcomes of multi-hole self-expandable metal stents versus fully covered self-expandable metal stents for malignant distal biliary obstruction in unresectable pancreatic cancer.

Tsuyoshi Takeda, Takashi Sasaki, Takeshi Okamoto, Takafumi Mie, Yoichiro Sato, Yuri Maegawa, Tatsuki Hirai, Yukari Suzuki, Takaaki Furukawa, Masato Ozaka and 1 more

Abstract read
In one paragraph

Article in DEN open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tsuyoshi TakedaDepartment of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.ORCID https://orcid.org/0000-0002-0786-8166
Takashi SasakiDepartment of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.
Takeshi OkamotoDepartment of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.
Takafumi MieDepartment of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.ORCID https://orcid.org/0000-0002-7561-5558
Yoichiro SatoDepartment of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.
Yuri MaegawaDepartment of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.
Tatsuki HiraiDepartment of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.
Yukari SuzukiDepartment of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.
Takaaki FurukawaDepartment of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.
Masato OzakaDepartment of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.
Naoki SasahiraDepartment of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The multi-hole self-expandable metal stent (MHSEMS) is a novel SEMS with multiple small side holes on the covering membrane to prevent stent migration while minimizing tumor ingrowth. This study aimed to evaluate the clinical outcomes of MHSEMS in comparison with conventional covered SEMS (c-CMS). Methods: Consecutive patients with unresectable pancreatic cancer who underwent initial SEMS placement (MHSEMS or c-CMS) for malignant distal biliary obstruction were analyzed. Technical success, clinical success, causes of recurrent biliary obstruction (RBO), non-RBO adverse events, time to RBO (TRBO), and endoscopic reintervention were compared between groups. Results: A total of 65 patients were included (MHSEMS: 27, c-CMS: 38). The technical success, clinical success, and non-RBO adverse event rates were similar between groups. Although stent migration was less frequently observed in the MHSEMS group (0% vs. 17.6%, Conclusions: MHSEMS was associated with a significantly shorter TRBO compared to c-CMS. Further modifications of the present MHSEMS may be needed.

Indexed as

covered self‐expandable metal stentendoscopic biliary drainageendoscopic biliary stentingmalignant distal biliary obstructionpancreatic cancer

Identifiers

PMID39323619
PMCPMC11422663

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.