Evidence map›Paper›PMID 39323550›Full record

ReviewRoyal Society open science2024

The roles of TAF1 in neuroscience and beyond.

Elisa M Crombie, Karen Cleverley, H T Marc Timmers, Elizabeth M C Fisher

Abstract readReview
In one paragraph

Review in Royal Society open science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. A recently evolved TAF8 isoform arising from anbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elisa M CrombieDepartment of Neuromuscular Diseases, UCL Institute of Neurology, University College London, London WC1N 3BG, UK.ORCID https://orcid.org/0000-0003-4806-6140
Karen CleverleyDepartment of Neuromuscular Diseases, UCL Institute of Neurology, University College London, London WC1N 3BG, UK.ORCID https://orcid.org/0009-0007-2517-687X
H T Marc TimmersGerman Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany.ORCID https://orcid.org/0000-0001-7062-1417
Elizabeth M C FisherDepartment of Neuromuscular Diseases, UCL Institute of Neurology, University College London, London WC1N 3BG, UK.ORCID https://orcid.org/0000-0003-2850-9936

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transcriptional machinery is essential for gene expression and regulation; dysregulation of transcription can result in a range of pathologies, including neurodegeneration, cancer, developmental disorders and cardiovascular disease. A key component of RNA polymerase II-mediated transcription is the basal transcription factor IID, which is formed of the TATA box-binding protein (TBP) and 14 TBP-associated factors (TAFs), the largest of which is the TAF1 protein, encoded on the X chromosome (Xq13.1).

Indexed as

RNA polymerase IITAF1TATA box binding-protein (TBP)-associated factor 1TFIIDX-linked dystonia–parkinsonismX-linked intellectual disability

Identifiers

PMID39323550
PMCPMC11423858

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.