Evidence map›Paper›PMID 39323492›Full record

ArticleJournal of biomedical optics2024

Exploring the impact and influence of melanin on frequency-domain near-infrared spectroscopy measurements.

Shidhartho Roy, Jingyi Wu, Jiaming Cao, Joel Disu, Sharadhi Bharadwaj, Elizabeth Meinert-Spyker, Pulkit Grover, Jana M Kainerstorfer, Sossena Wood

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Regional oximetry for diagnosing compartment syndrome: a scoping review.Journal of orthopaedic surgery and research · 2026
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shidhartho RoyCarnegie Mellon University, Department of Biomedical Engineering, Pittsburgh, Pennsylvania, United States.ORCID 0000-0001-8448-0790
Jingyi WuCarnegie Mellon University, Department of Biomedical Engineering, Pittsburgh, Pennsylvania, United States.ORCID 0000-0003-3666-5082
Jiaming CaoCarnegie Mellon University, Department of Biomedical Engineering, Pittsburgh, Pennsylvania, United States.ORCID 0000-0002-2766-5788
Joel DisuCarnegie Mellon University, Department of Biomedical Engineering, Pittsburgh, Pennsylvania, United States.ORCID 0009-0003-1795-7861
Sharadhi BharadwajCarnegie Mellon University, Department of Biomedical Engineering, Pittsburgh, Pennsylvania, United States.
Elizabeth Meinert-SpykerCarnegie Mellon University, Department of Biomedical Engineering, Pittsburgh, Pennsylvania, United States.
Pulkit GroverCarnegie Mellon University, Department of Biomedical Engineering, Pittsburgh, Pennsylvania, United States.
Jana M KainerstorferCarnegie Mellon University, Department of Biomedical Engineering, Pittsburgh, Pennsylvania, United States.ORCID 0000-0002-9481-8377
Sossena WoodCarnegie Mellon University, Department of Biomedical Engineering, Pittsburgh, Pennsylvania, United States.ORCID 0000-0003-3079-1096

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: Near-infrared spectroscopy (NIRS) is a non-invasive optical method that measures changes in hemoglobin concentration and oxygenation. The measured light intensity is susceptible to reduced signal quality due to the presence of melanin. Aim: We quantify the influence of melanin concentration on NIRS measurements taken with a frequency-domain near-infrared spectroscopy system using 690 and 830 nm. Approach: Using a forehead NIRS probe, we measured 35 healthy participants and investigated the correlation between melanin concentration indices, which were determined using a colorimeter, and several key metrics from the NIRS signal. These metrics include signal-to-noise ratio (SNR), two measurements of oxygen saturation (arterial oxygen saturation, Results: We found a significant negative correlation between the melanin index and the SNR estimated in oxy-hemoglobin signals ( Conclusions: We found that estimated SNR and

Indexed as

MelaninsSignal-To-Noise RatioSpectroscopy, Near-InfraredAdultFemaleHemoglobinsHumansMaleOximetryOxygenOxygen SaturationOxyhemoglobinsYoung AdultHemoglobinsMelaninsOxygenOxyhemoglobinsmelanin indexnear-infrared spectroscopyoptical propertiesoxygen saturationsignal-to-noise ratio

Identifiers

PMID39323492
PMCPMC11423252

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.