Evidence map›Paper›PMID 39323348›Full record

ReviewMini reviews in medicinal chemistry2025

Trace Elements in Medicinal Metallomics.

Marina Orlova, Stepan Kalmykov, Tatiana Trofimova, Dmitry Kuznetsov

Abstract readReview
PubMed Publisher
In one paragraph

Review in Mini reviews in medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Elemental Composition ofJournal of xenobiotics · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marina OrlovaDepartment of Chemistry, Lomonosov Moscow State University, Moscow, Leninskie Gory, 1, bld. 3, Russian Federation.
Stepan KalmykovDepartment of Chemistry, Lomonosov Moscow State University, Moscow, Leninskie Gory, 1, bld. 3, Russian Federation.
Tatiana TrofimovaDepartment of Chemistry, Lomonosov Moscow State University, Moscow, Leninskie Gory, 1, bld. 3, Russian Federation.
Dmitry KuznetsovMed.-Biol. Department, Pirogov Russian National Research Medical University, Moscow, Ostrovityanov St, 1, Russian Federation.

Funding

Ministry of Science and Higher Education of the Russian Federation 075-15-2024-553
6 · The paper itself

Abstract

This analytical mini-review focuses on the effects of trace elements, which includes Cu, Mn, Zn, and Se, as well as some rarer microelements, on the regulation of oxidative stress in the body and of certain diseases associated with it. Synergism and competition between certain microelements have been considered a hot topic in the applied molecular pharmacology of these specific bio-effects. Some ideas for further possible directions of research are expressed. Noteworthy, metal coordinating catalytical sites of certain enzymes function as pharmacophore-forming and connecting nanostructures. These sites can be regarded as targets for various effectors, making them pharmacologically significant contributors to biocatalysis.

Indexed as

Trace ElementsAnimalsHumansOxidative StressTrace Elementsdrug targetsEnzymatic pharmacophoresmedicinal bio-organic chemistrymetal-dependent enzymesmetallomicstrace elements.

Identifiers

PMID39323348

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.