Evidence map›Paper›PMID 39322915›Full record

ArticleCanadian journal of public health = Revue canadienne de sante publique2024

Routine vaccine uptake in school-aged autistic and non-autistic youth: A linked database study.

Linda Dodds, Christopher Filliter, Leslie Anne Campbell, Noni E MacDonald, Sarah Shea, Eve Dubé, Isabel M Smith, Azar Mehrabadi, Jillian H Filliter

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Article in Canadian journal of public health = Revue canadienne de sante publique, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Linda DoddsDepartment of Pediatrics, Dalhousie University, Halifax, NS, Canada. l.dodds@dal.ca.
Christopher FilliterIWK Health Centre, Halifax, NS, Canada.
Leslie Anne CampbellIWK Health Centre, Halifax, NS, Canada.
Noni E MacDonaldDepartment of Pediatrics, Dalhousie University, Halifax, NS, Canada.
Sarah SheaDepartment of Pediatrics, Dalhousie University, Halifax, NS, Canada.
Eve DubéInstitut National de Santé Publique du Québec, Québec, QC, Canada.
Isabel M SmithDepartment of Pediatrics, Dalhousie University, Halifax, NS, Canada.
Azar MehrabadiDepartment of Pediatrics, Dalhousie University, Halifax, NS, Canada.
Jillian H FilliterDepartment of Pediatrics, Dalhousie University, Halifax, NS, Canada.

Funding

Nova Scotia Health Research Foundation 754
6 · The paper itself

Abstract

objectivesThis study was conducted to determine whether school-aged autistic youth received routine vaccines at a lower rate than their non-autistic peers.

methodsIn Nova Scotia (NS), Canada, vaccines routinely delivered in early adolescence are administered to Grade 7 students through a school-based Public Health vaccination program. NS youth eligible to receive Grade 7 vaccinations between 2011 and 2017 were included in this study. Autism spectrum disorder (ASD) diagnoses were determined from administrative health data. Rates of receipt of any Grade 7 vaccine and of individual vaccines were compared between autistic and non-autistic youth. Subgroup analyses included comparing Grade 7 vaccine receipt between autistic youth and their non-autistic siblings and early childhood vaccine receipt between autistic and non-autistic cohorts.

resultsThe rates of receipt of any vaccine were 73% among 916 autistic youth and 82% among 49,599 non-autistic youth (adjusted relative risk = 0.91; 95% confidence interval = 0.87-0.95). Similar results were found for individual vaccines. Subgroup analyses revealed lower rates of Grade 7 vaccine receipt among autistic youth compared to among their non-autistic siblings. Rates of early childhood vaccine receipt did not differ between autistic and non-autistic cohorts.

conclusionAutistic youth were under-vaccinated compared to their non-autistic peers for Grade 7 vaccinations. Lower vaccination rates in autistic youth than in their non-autistic siblings suggest that setting-related factors may contribute more to the under-vaccination of autistic youth than parental vaccine hesitancy. Barriers to vaccine uptake for school-aged autistic youth, including those unique to school-based vaccination programs, must be explored and addressed.

Indexed as

Autism Spectrum DisorderVaccination CoverageChildCohort StudiesDiphtheria-Tetanus-acellular Pertussis VaccinesHepatitis B VaccinesHumansInformed ConsentMeningococcal VaccinesNova ScotiaPapillomavirus VaccinesRetrospective StudiesSchoolsVaccinationDiphtheria-Tetanus-acellular Pertussis VaccinesHepatitis B VaccinesMeningococcal VaccinesPapillomavirus VaccinesAutism spectrum disorderPublic health school-based vaccinesVaccineYouth

Identifiers

PMID39322915
PMCPMC11644134

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.