Evidence map›Paper›PMID 39322817›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2024

Seroma incidence and risk factors in women undergoing mastectomies as surgical breast cancer treatment.

Erica Alves Nogueira Fabro, Rejane Medeiros Costa, Maíra Carneiro Fernandes, Matheus Albino Ximenes, Denismar Alves Nogueira, Nathalia Bordinhon Soares, Luiz Claudio Santos Thuler, Anke Bergmann

Registry-linked trialAbstract read
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In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04471142 (Effectiveness of Compressive Bandage Use in Post-Treatment Seroma Prevention Breast Cancer Surgery), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04471142 naunknown statusnot on this map

Effectiveness of Compressive Bandage Use in Post-Treatment Seroma Prevention Breast Cancer Surgery

TypeinterventionalSponsorInstituto Nacional de Cancer, BrazilRan2021 to 2023Enrolled270ConditionsSeromaArmsneuromuscular bandage
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Erica Alves Nogueira FabroPhysiotherapy Service, Cancer Hospital III, National Cancer Institute, Visconde de Santa Isabel Street, 274 - Vila Isabel, Rio de Janeiro, 20560-120, Brazil. efabro@inca.gov.br.ORCID http://orcid.org/0000-0003-0959-7678
Rejane Medeiros CostaPhysiotherapy Service, Cancer Hospital III, National Cancer Institute, Visconde de Santa Isabel Street, 274 - Vila Isabel, Rio de Janeiro, 20560-120, Brazil.ORCID http://orcid.org/0000-0002-8195-955X
Maíra Carneiro FernandesPhysiotherapy Service, Cancer Hospital III, National Cancer Institute, Visconde de Santa Isabel Street, 274 - Vila Isabel, Rio de Janeiro, 20560-120, Brazil.ORCID http://orcid.org/0009-0000-8799-7760
Matheus Albino XimenesPhysiotherapy Service, Cancer Hospital III, National Cancer Institute, Visconde de Santa Isabel Street, 274 - Vila Isabel, Rio de Janeiro, 20560-120, Brazil.ORCID http://orcid.org/0000-0003-2064-9336
Denismar Alves NogueiraInstitute of Exact Sciences, Federal University of Alfenas, Alfenas, Minas Gerais, Brazil.ORCID http://orcid.org/0000-0003-2285-8764
Nathalia Bordinhon SoaresPhysiotherapy Service, Cancer Hospital III, National Cancer Institute, Visconde de Santa Isabel Street, 274 - Vila Isabel, Rio de Janeiro, 20560-120, Brazil.ORCID http://orcid.org/0000-0003-3667-7331
Luiz Claudio Santos ThulerClinical Epidemiology Program, National Cancer Institute, Rio de Janeiro, Brazil.ORCID http://orcid.org/0000-0003-2550-6537
Anke BergmannClinical Epidemiology Program, National Cancer Institute, Rio de Janeiro, Brazil.ORCID http://orcid.org/0000-0002-1972-8777

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSeroma is the most common early complication following surgical breast cancer treatment. Its development is associated with pain, scar complications, adjuvant therapy delays, the need for outpatient visits, and increased care costs.

objectiveAssess seroma incidence and risk factors in women undergoing mastectomies.

methodThis study comprises a prospective cohort encompassing women aged 18 or over undergoing mastectomies as a breast cancer treatment. Patients underwent physiotherapy on the 1st, 7th, and 30th postoperative days for kinetic-functional, skin, and wound healing assessments and were attended to by nurses for surgical wound care, draining liquid on the 7th, 14th, and 21st postoperative days. Seroma was defined as the presence of local fluctuations requiring puncture, regardless of the punctured volume.

resultsA total of 249 women were evaluated, with a mean age of 57.5 (SD = 11.8). A total of 77.1% were classified as overweight or obese, 60.2% were hypertensive, 21.3% were diabetic, 66.7% underwent neoadjuvant chemotherapy and 62.7% underwent axillary lymphadenectomies. Seroma incidence was 71.1%, requiring, on average, two aspiration punctures until condition resolution. Overweight or obese women and those who underwent axillary lymphadenectomies exhibited 1.92- and 2.06-fold higher risk for seroma development (OR = 1.92; 95% CI 1.02-3.61; p = 0.042; and OR = 2.06; 95% CI 1.17-3.63; p = 0.012), respectively.

conclusionSeroma incidence was very high. Being overweight or obese and undergoing axillary lymphadenectomy comprise independent seroma development risk factors. This study is part of a randomized clinical trial evaluating the effectiveness of applying compressive taping to prevent post-mastectomy seroma, which was approved by the Brazilian National Cancer Institute, Research Ethics Committee (2,774,824), and it is registered in the ClinicalTrials.gov (NCT04471142, on July 15, 2020).

Indexed as

Breast NeoplasmsMastectomySeromaAdultAgedCohort StudiesFemaleHumansIncidenceLymph Node ExcisionMiddle AgedPostoperative ComplicationsProspective StudiesRisk FactorsBreast cancerMastectomySeroma

Identifiers

PMID39322817

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.