Evidence map›Paper›PMID 39322760›Full record

ArticleThe EMBO journal2024

m

Sevim Kahraman, Dario F De Jesus, Jiangbo Wei, Natalie K Brown, Zhongyu Zou, Jiang Hu, Mehdi Pirouz, Richard I Gregory, Chuan He, Rohit N Kulkarni

Abstract read
In one paragraph

Article in The EMBO journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. RNA mActa pharmacologica Sinica · 2026
    Review
  2. Article
  3. mNature metabolism · 2026
    Article
  4. Review
  5. Article
  6. Mechanisms of gypenosides in type 2 diabetes mellitus via regulation of m6A methylase METTL3/14 and demethylase FTO.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article
  7. Targeting RNA adenosine editing and modification enzymes for RNA therapeutics.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  8. Article
  9. Divergent roles of mNature communications · 2025
    Article
  10. Review
  11. mCell metabolism · 2024
    Article
4 · The record

Corrections and comments

  • Update of
    m2023
5 · Who and what money

Authors and funding

10 authors.

Sevim Kahraman *Islet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, MA, USA.
Dario F De Jesus *Islet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, MA, USA.ORCID http://orcid.org/0000-0001-8826-9095
Jiangbo Wei *Department of Chemistry, Department of Biochemistry and Molecular Biology, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, 60637, USA.
Natalie K BrownIslet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, MA, USA.ORCID http://orcid.org/0000-0002-9984-0135
Zhongyu ZouDepartment of Chemistry, Department of Biochemistry and Molecular Biology, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, 60637, USA.
Jiang HuIslet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, MA, USA.
Mehdi PirouzHarvard Stem Cell Institute, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-7439-6066
Richard I GregoryHarvard Stem Cell Institute, Harvard Medical School, Boston, MA, USA.
Chuan HeDepartment of Chemistry, Department of Biochemistry and Molecular Biology, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, 60637, USA.ORCID http://orcid.org/0000-0003-4319-7424
Rohit N KulkarniIslet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, MA, USA. Rohit.Kulkarni@joslin.harvard.edu.ORCID http://orcid.org/0000-0001-5029-6119

Funding

VectorP30CA006516 · NCI · DANA-FARBER CANCER INSTITUTE · PI Irene M. Ghobrial · 1985 to 2026
$330.6M
SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI ROHIT N. KULKARNI · 1986 to 2026
$50.5M
Transcriptome-wide base-resolution sequencing of pseudouridine in human normal and AD brain tissues-CEGS Admin supplement 2020-2021RM1HG008935 · NHGRI · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2016 to 2025
$24.4M
Role of IGF-1 and Insulin Receptors Beta-Cell SurvivalR01DK067536 · NIDDK · JOSLIN DIABETES CENTER · PI ROHIT N. KULKARNI · 2004 to 2026
$8.0M
Role of the Epitranscriptome in CancerR35CA232115 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GREGORY, RICHARD I. · 2019 to 2025
$7.2M
Epitranscriptomics in human obesity and type 2 diabetesRC2DK139552 · NIDDK · JOSLIN DIABETES CENTER · PI Mengjie Chen, CHUAN HE · 2024 to 2026
$6.0M
Interrogation of dynamic RNA modifications in beta cells in type 1 diabetesUC4DK116278 · NIDDK · JOSLIN DIABETES CENTER · PI HE, CHUAN, KULKARNI, ROHIT N. · 2017 to 2017
$1.9M
Interrogating the role of m6A mRNA methylation in the aging of the β-cell and diabetesR00DK135927 · NIDDK · UNIVERSITY OF CHICAGO · PI Dario F De Jesus · 2025 to 2026
$498k
Special BD LSRFortessaS10OD021740 · OD · JOSLIN DIABETES CENTER · PI SERWOLD, THOMAS F · 2016 to 2016
$363k
Interrogating the role of m6A mRNA methylation in the aging of the β-cell and diabetesK99DK135927 · NIDDK · JOSLIN DIABETES CENTER · PI F DE JESUS, DARIO · 2023 to 2024
$180k
American Diabetes Association (ADA) 7-21-PDF-140Diabetes Research Wellness Foundation (DRWF) Endowed ChairHHS | NIH | National Cancer Institute (NCI) R35CA232115Howard Hughes Medical Institute (HHMI) InvestigatorNCI NIH HHS P30 CA006516NCI NIH HHS R35 CA232115NHGRI NIH HHS RM1 HG008935NIDDK NIH HHS K99 DK135927NIDDK NIH HHS P30 DK036836NIDDK NIH HHS R00 DK135927NIDDK NIH HHS R01 DK067536NIDDK NIH HHS RC2 DK139552NIDDK NIH HHS UC4 DK116278NIH HHS S10 OD021740
6 · The paper itself

Abstract

N

Indexed as

AdenosineCell DifferentiationMethyltransferasesPancreasRNA, MessengerAnimalsHumansMethylationMiceAdenosineMethyltransferasesMETTL14 protein, humanMettl14 protein, mouseN-methyladenosineRNA, MessengerDuct CellsHuman Pancreas Developmentm6A mRNA Methylationα-cellsβ-cells

Identifiers

PMID39322760
PMCPMC11574190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.