Evidence map›Paper›PMID 39322680›Full record

ArticleNature2024

Structural basis of archaeal FttA-dependent transcription termination.

Linlin You, Chengyuan Wang, Vadim Molodtsov, Konstantin Kuznedelov, Xinyi Miao, Breanna R Wenck, Paul Ulisse, Travis J Sanders, Craig J Marshall, Emre Firlar and 3 more

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Archaeal RNA processing and regulation: expanding the functional landscape.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Toward structural understanding of eukaryotic transcription elongation.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2025
    Review
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Linlin You *Waksman Institute and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, USA.
Chengyuan Wang *Waksman Institute and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, USA.ORCID 0000-0002-8605-0716
Vadim Molodtsov *Waksman Institute and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, USA.ORCID 0000-0003-3002-4794
Konstantin KuznedelovWaksman Institute and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, USA.ORCID 0000-0002-9040-3895
Xinyi MiaoWaksman Institute and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, USA.ORCID 0009-0000-0692-7534
Breanna R WenckDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.
Paul UlisseDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.
Travis J SandersDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.
Craig J MarshallDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.
Emre FirlarRutgers CryoEM and Nanoimaging Facility and Institute for Quantitative Biomedicine, Rutgers University, Piscataway, NJ, USA.
Jason T KaelberRutgers CryoEM and Nanoimaging Facility and Institute for Quantitative Biomedicine, Rutgers University, Piscataway, NJ, USA.ORCID 0000-0001-9426-1030
Thomas J SantangeloDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.ORCID 0000-0003-4559-3244
Richard H EbrightWaksman Institute and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, USA. ebright@waksman.rutgers.edu.ORCID 0000-0001-8915-7140

Funding

NCCAT: National Center for CryoEM Access and Training- Supplement for Windows 10 and FFIU24GM129539 · NIGMS · NEW YORK STRUCTURAL BIOLOGY CENTER · PI DE MARCO, ALEX, KIEFT, JEFFREY S · 2018 to 2023
$53.9M
Transcription: Mechanism and RegulationR35GM118059 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI NICKELS, BRYCE EDWARD · 2016 to 2025
$7.1M
TRANSCRIPTION ACTIVATION BY CAPR01GM041376 · NIGMS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI RICHARD H. EBRIGHT · 1989 to 2026
$6.5M
BACTERIAL TRANSCRIPTION COMPLEXESR37GM041376 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI EBRIGHT, RICHARD H. · 2013 to 2022
$5.0M
Mechanisms of Archaeal Transcription Termination - Administrative SupplementR01GM100329 · NIGMS · OHIO STATE UNIVERSITY · PI SANTANGELO, THOMAS JAMES · 2012 to 2021
$2.5M
Regulation of Archaeal TranscriptionR35GM143963 · NIGMS · COLORADO STATE UNIVERSITY · PI Thomas James Santangelo · 2022 to 2026
$1.8M
NIGMS NIH HHS R01 GM041376NIGMS NIH HHS R01 GM100329NIGMS NIH HHS R35 GM118059NIGMS NIH HHS R35 GM143963NIGMS NIH HHS R37 GM041376NIGMS NIH HHS U24 GM129539
6 · The paper itself

Abstract

The ribonuclease FttA (also known as aCPSF and aCPSF1) mediates factor-dependent transcription termination in archaea

Indexed as

Archaeal ProteinsRibonucleasesThermococcusTranscriptional Elongation FactorsTranscription Termination, GeneticBacteriaCatalytic DomainChromosomal Proteins, Non-HistoneCryoelectron MicroscopyEukaryotaEvolution, MolecularModels, MolecularRNA, ArchaealArchaeal ProteinsChromosomal Proteins, Non-HistoneRibonucleasesRNA, ArchaealSPT5 transcriptional elongation factorTranscriptional Elongation Factors

Identifiers

PMID39322680
PMCPMC11616081

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.