Evidence map›Paper›PMID 39322671›Full record

ArticleNature2024

Human hippocampal and entorhinal neurons encode the temporal structure of experience.

Pawel Tacikowski, Güldamla Kalender, Davide Ciliberti, Itzhak Fried

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Learning of visual sequences by neurons in the human hippocampus.bioRxiv : the preprint server for biology · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Time, space, memory and brain-body rhythms.Nature reviews. Neuroscience · 2026
    Review
  13. Review
  14. Article
  15. Neural Representation of Episodic Time.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Review
  16. Trial-by-trial learning of successor representations in human behavior.bioRxiv : the preprint server for biology · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pawel TacikowskiDepartment of Neurosurgery, University of California, Los Angeles, Los Angeles, CA, USA. paweltacikowski@gmail.com.ORCID 0000-0003-2434-2112
Güldamla KalenderDepartment of Neurosurgery, University of California, Los Angeles, Los Angeles, CA, USA.
Davide CilibertiDepartment of Neurosurgery, University of California, Los Angeles, Los Angeles, CA, USA.ORCID 0000-0003-1229-642X
Itzhak FriedDepartment of Neurosurgery, University of California, Los Angeles, Los Angeles, CA, USA. ifried@mednet.ucla.edu.ORCID 0000-0002-5962-2678

Funding

Decoding and Selective Modulation of Human Memory During Awake/Sleep CyclesU01NS123128 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FRIED, ITZHAK · 2021 to 2025
$7.1M
Mechanisms of Memory Enhancement by Deep Brain Stimulation in HumansR01NS084017 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FRIED, ITZHAK · 2013 to 2022
$4.7M
Memory consolidation during sleep studied by direct neuronal recording and stimulation inside human brainU01NS108930 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FRIED, ITZHAK · 2018 to 2019
$1.9M
NINDS NIH HHS R01 NS084017NINDS NIH HHS U01 NS108930NINDS NIH HHS U01 NS123128
6 · The paper itself

Abstract

Extracting the underlying temporal structure of experience is a fundamental aspect of learning and memory that allows us to predict what is likely to happen next. Current knowledge about the neural underpinnings of this cognitive process in humans stems from functional neuroimaging research

Indexed as

Entorhinal CortexHippocampusMemory, EpisodicModels, NeurologicalNeuronsAdultElectrodes, ImplantedFemaleHumansMaleTime FactorsYoung Adult

Identifiers

PMID39322671
PMCPMC11540853

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.