Evidence map›Paper›PMID 39322631›Full record

ArticleESC heart failure2024

Prognostic value of estimated plasma volume status at discharge in acute myocardial infarction.

Kazutaka Nogi, Tomoya Ueda, Maki Nogi, Satomi Ishihara, Yasuki Nakada, Yukihiro Hashimoto, Hitoshi Nakagawa, Taku Nishida, Ayako Seno, Kenji Onoue and 3 more

Abstract read
In one paragraph

Article in ESC heart failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kazutaka NogiDepartment of Cardiovascular Medicine, Nara Medical University, Kashihara, Japan.
Tomoya UedaDepartment of Cardiovascular Medicine, Nara Medical University, Kashihara, Japan.
Maki NogiDepartment of Cardiovascular Medicine, Nara Medical University, Kashihara, Japan.
Satomi IshiharaDepartment of Cardiovascular Medicine, Nara Medical University, Kashihara, Japan.
Yasuki NakadaDepartment of Cardiovascular Medicine, Nara Medical University, Kashihara, Japan.
Yukihiro HashimotoDepartment of Cardiovascular Medicine, Nara Medical University, Kashihara, Japan.
Hitoshi NakagawaDepartment of Cardiovascular Medicine, Nara Medical University, Kashihara, Japan.
Taku NishidaDepartment of Cardiovascular Medicine, Nara Medical University, Kashihara, Japan.
Ayako SenoDepartment of Cardiovascular Medicine, Nara Medical University, Kashihara, Japan.
Kenji OnoueDepartment of Cardiovascular Medicine, Nara Medical University, Kashihara, Japan.
Makoto WatanabeDepartment of Cardiovascular Medicine, Nara Medical University, Kashihara, Japan.
Yoshihiko SaitoDepartment of Cardiovascular Medicine, Nara Medical University, Kashihara, Japan.
Shungo HikosoDepartment of Cardiovascular Medicine, Nara Medical University, Kashihara, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsCongestive heart failure (HF) is a common complication in patients with acute myocardial infarction (AMI). The estimated plasma volume status [ePVS = (100 - haematocrit)/haemoglobin] is used as the blood plasma volume index to determine the presence of congestion in patients with HF. However, the clinical impact of ePVS at discharge in patients with AMI remains unclear. This study aimed to investigate whether ePVS at discharge could determine the long-term prognosis in patients with AMI. METHODS AND

resultsWe retrospectively identified patients with AMI with ePVS measured at discharge between January 2012 and December 2020. The primary endpoint was post-discharge all-cause death. The patients were divided into two groups according to an ePVS cut-off value of 5.5%, which is commonly used in HF. In total, 1012 patients with AMI were included. The median age was 70 years (range, 61-78 years), and 76.4% of the patients were male. The ePVS > 5.5% (high-ePVS) group included 365 patients (36.1%), and the all-cause mortality rate in the total cohort was 17.7%. The log-rank test revealed that the high-ePVS group had a significantly higher rate of all-cause death than the ePVS ≤ 5.5% (low-ePVS) group (P < 0.001). Multivariate Cox proportional hazards model analysis revealed that high ePVS was associated with post-discharge all-cause death, independent of other risk factors (hazard ratio = 1.879; 95% confidence interval = 1.343-2.629, P < 0.001).

conclusionsHigh ePVS at discharge was independently associated with high post-discharge all-cause mortality in patients with AMI. Our study suggests that ePVS at discharge in patients with AMI could serve as a novel prognostic marker.

Indexed as

Myocardial InfarctionPatient DischargePlasma VolumeAgedCause of DeathFemaleFollow-Up StudiesHeart FailureHumansMaleMiddle AgedPrognosisRetrospective StudiesSurvival RateCongestionEstimated plasma volume statusHeart failureMyocardial infarction

Identifiers

PMID39322631
PMCPMC11424303

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.