Evidence map›Paper›PMID 39322568›Full record

ArticleMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine2025

Characterizing Protein Concentration in Cerebrospinal Fluid with T

Tatsuya Koizumi, Seiko Shimizu, Chihiro Akiba, Hidenori Kakizoe, Hideki Bandai, Kenichi Sato, Hidekazu Nagasawa, Ikuko Ogino, Madoka Nakajima, Shinya Yamada and 2 more

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Article in Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tatsuya KoizumiDepartment of Radiology, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, Japan.
Seiko ShimizuCanon Medical Systems Corporation, Otawara, Tochigi, Japan.
Chihiro AkibaDepartment of Neurosurgery, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, Japan.
Hidenori KakizoeDepartment of Radiology, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, Japan.
Hideki BandaiDepartment of Neurosurgery, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, Japan.
Kenichi SatoDepartment of Radiology, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, Japan.
Hidekazu NagasawaDepartment of Radiology, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, Japan.
Ikuko OginoDepartment of Neurosurgery, Juntendo University, Tokyo, Japan.
Madoka NakajimaDepartment of Neurosurgery, Juntendo University, Tokyo, Japan.
Shinya YamadaDepartment of Neurosurgery, Juntendo University, Tokyo, Japan.
Koichi OshioDepartment of Radiology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Masakazu MiyajimaDepartment of Neurosurgery, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeT

methodsWe first dissolved 1.2g of bovine serum albumin powder in 4 mL of artificial CSF to purify an albumin solution with a concentration of 4.5 mM. Artificial CSF was added thereto, and eight types of albumin solutions, with concentrations of 0.002-4.5 mM, were purified. We acquired this albumin solution with CPMG pulses and NNLS, decomposed the T

resultsT

conclusionThe present method with CPMG sequences and NNLS provide adequate images to differentiate accumulating protein concentrations in the CSF, even at the level of a single pixel.

Indexed as

Cerebrospinal Fluid ProteinsMagnetic Resonance ImagingHumansLeast-Squares AnalysisSerum Albumin, BovineCerebrospinal Fluid ProteinsSerum Albumin, BovineCarr-Purcell-Meiboom-Gilcerebrospinal fluidglymphatic systemnon-negative least squaresT2 map

Identifiers

PMID39322568
PMCPMC12557878

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.