Evidence map›Paper›PMID 39322554›Full record

ArticleAnnals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia2024

Midterm Clinical Outcomes after Isolated Surgical and Transcatheter Aortic Valve Replacement in Low-Risk Patients with Aortic Stenosis.

Kazuma Handa, Koichi Maeda, Kyongsun Pak, Kazuo Shimamura, Kizuku Yamashita, Ai Kawamura, Shigeru Miyagawa

Abstract readComparative StudyMulticenter Study
In one paragraph

Article in Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kazuma HandaDepartment of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.ORCID http://orcid.org/0000-0002-6080-2166
Koichi MaedaDepartment of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.ORCID http://orcid.org/0000-0002-1102-111X
Kyongsun PakDivision of Biostatistics, Center for Clinical Research, National Center for Child Health and Development, Tokyo, Japan.
Kazuo ShimamuraDepartment of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Kizuku YamashitaDepartment of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Ai KawamuraDepartment of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Shigeru MiyagawaDepartment of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to compare the clinical outcomes of isolated surgical aortic valve replacement (SAVR) and transfemoral (TF)-transcatheter aortic valve replacement (TAVR) in low-risk aortic stenosis (AS) patients.

methodsA total of 696 low-risk (Society of Thoracic Surgeons score <4%) AS patients underwent isolated SAVR or TF-TAVR at five centers. After 1:1 propensity score matching, 159 pairs were identified. Early and follow-up events, including cardiac mortality and major adverse cardiac and cerebrovascular events (MACCE: all-cause mortality, heart failure admission, reoperation, prosthetic valve endocarditis, and stroke), were compared.

resultsBaseline characteristics are similar between the matched groups. There were no 30-day cardiac mortalities in either group. All-cause mortality and MACCE at 30 days did not differ. During 5-year follow-up (median 3.1 [range 0-7.2] years), the incidence of cardiac mortality (1.3% vs. 18.9%; adjusted hazard ratio [aHR], 8.89; 95% confidence interval [CI], 2.68-29.53; P <0.001), all-cause mortality (4.2% vs. 33.9%; aHR, 8.56; 95% CI, 3.41-21.45; P <0.001), and MACCE (25.1% vs. 47.0%; aHR, 2.36; 95% CI, 1.54-3.63; P <0.001) were lower in the SAVR group than in the TAVR group.

conclusionsIsolated SAVR demonstrated better outcomes in low-risk AS patients. TAVR in this subset should be chosen carefully.

Indexed as

Aortic ValveAortic Valve StenosisHeart Valve Prosthesis ImplantationPostoperative ComplicationsTranscatheter Aortic Valve ReplacementAgedAged, 80 and overCatheterization, PeripheralFemaleHumansKaplan-Meier EstimateMaleMiddle AgedPropensity ScoreRetrospective StudiesRisk Assessmentaortic stenosissurgical aortic valve replacementtranscatheter aortic valve replacement

Identifiers

PMID39322554
PMCPMC11439598

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.