Evidence map›Paper›PMID 39322316›Full record

Observational studyArchives of disease in childhood. Fetal and neonatal edition2025

Fetal haemoglobin and oxygen requirement in preterm infants: an observational study.

Tommy Ulinder, William Hellström, Christian Gadsbøll, Linda Nilsson, Margareta Gebka, Gustav Robertz, Matteo Bruschettini, Ann Hellstrom, David Ley

Abstract readObservational Study
In one paragraph

Observational study in Archives of disease in childhood. Fetal and neonatal edition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Assessment of iron sufficiency in premature infants treated with darbepoetin using conventional and novel erythrocyte metrics.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  3. Review
  4. Article
  5. Cardiorespiratory transition in CDH.Seminars in fetal & neonatal medicine · 2025
    Review
  6. How Delayed Cord Clamping Saves Newborn Lives.Children (Basel, Switzerland) · 2025
    Review
  7. Minimizing blood sampling in preterm infants.The Cochrane database of systematic reviews · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tommy UlinderDepartment of Clinical Sciences Lund, Paediatrics, Lund University, Lund, Sweden tommy.ulinder@med.lu.se.ORCID http://orcid.org/0009-0007-5588-6661
William HellströmDepartment of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID http://orcid.org/0000-0001-6669-260X
Christian GadsbøllDepartment of Clinical Sciences Lund, Paediatrics, Lund University, Skane University Hospital, Lund, Sweden.
Linda NilssonDepartment of Clinical Sciences Lund, Paediatrics, Lund University, Skane University Hospital, Lund, Sweden.
Margareta GebkaDepartment of Clinical Sciences Lund, Paediatrics, Lund University, Skane University Hospital, Lund, Sweden.
Gustav RobertzDepartment of Paediatrics, Ystad Hospital, Ystad, Sweden.
Matteo BruschettiniSkåne University Hospital, Lund, Sweden.ORCID http://orcid.org/0000-0002-4775-872X
Ann HellstromOphthalmology, Sahlgrenska Academy, Goteborg, Sweden.ORCID http://orcid.org/0000-0002-9259-1244
David LeyDepartment of Clinical Sciences Lund, Paediatrics, Lund University, Skane University Hospital, Lund, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the relationship between the fraction of fetal haemoglobin (HbF(%)) and oxygen requirement as determined by the fraction of inspired oxygen (FiO

designLongitudinal, retrospective, observational study.

settingTertiary-level neonatal intensive care unit, referral centre for southern Sweden. PATIENTS: Four hundred forty very preterm infants born before gestational week 30, 2009-2015.

interventionRegular clinical practice.

main outcome measuresThe FiO

resultsWe found a significant relationship between a low fraction of HbF and an increase in FiO

conclusionThese high-resolution data show that decreased HbF(%) during the first postnatal week is associated with increased FiO

Indexed as

Bronchopulmonary DysplasiaFetal HemoglobinInfant, PrematureOxygenOxygen Inhalation TherapyBlood Gas AnalysisFemaleGestational AgeHumansInfant, NewbornIntensive Care Units, NeonatalLongitudinal StudiesMaleRetrospective StudiesSwedenFetal HemoglobinOxygenIntensive Care Units, NeonatalNeonatologyPaediatrics

Identifiers

PMID39322316
PMCPMC12013580

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.