Evidence map›Paper›PMID 39322312›Full record

ArticleJournal of sleep research2025

Association between lung function and sleep disorder symptoms in a community-based multi-site case-finding study.

Rosetta Mazzola, Shawn D Aaron, Katherine L Vandemheen, Sunita Mulpuru, Celine Bergeron, Catherine Lemière, Andréanne Côté, Louis-Philippe Boulet, Stephen K Field, Erika Penz and 11 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of sleep research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Rosetta MazzolaDepartment of Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.ORCID 0009-0003-8563-4888
Shawn D AaronDepartment of Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Katherine L VandemheenThe Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Sunita MulpuruDepartment of Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Celine BergeronDepartment of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Catherine LemièreDepartment of Medicine, Université de Montreal, Pavillon Roger-Gaudry, Montreal, Quebec, Canada.
Andréanne CôtéInstitut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Quebec City, Québec, Canada.
Louis-Philippe BouletInstitut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Quebec City, Québec, Canada.
Stephen K FieldCumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Erika PenzDepartment of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
R Andrew McIvorFirestone Institute for Respiratory Health, McMaster University, Hamilton, Ontario, Canada.
Samir GuptaDepartment of Medicine, University of Toronto, Toronto, Ontario, Canada.
Irvin MayersDepartment of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Mohit BhutaniDepartment of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Paul HernandezDepartment of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
M Diane LougheedDepartment of Medicine, Queen's University, Kingston, Ontario, Canada.
Christopher J LicskaiDepartment of Medicine, University of Western Ontario, London, Ontario, Canada.
Tanweer AzherDepartment of Medicine, Memorial University, St John's, Newfoundland and Labrador, Canada.
Nicole EzerDepartment of Medicine, McGill University, Montreal, Quebec, Canada.
Martha AinslieDepartment of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Tetyana KendzerskaDepartment of Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.ORCID 0000-0002-5301-1796

Funding

CIHR 154322
6 · The paper itself

Abstract

Obstructive airway disease is associated with sleep disturbances. We aimed to assess the relationship between lung function and sleep disorder symptoms using cross-sectionally collected data between March 2017 and August 2021 from the Undiagnosed Chronic Obstructive Pulmonary Disease and Asthma Population study, a prospective community-based multi-site case-finding study. Undiagnosed Chronic Obstructive Pulmonary Disease and Asthma Population study participants with respiratory symptoms but without diagnosed lung disease who completed spirometry and the Global Sleep Assessment Questionnaire were included. We conducted multivariate linear regression models for forced expiratory volume in 1 s, forced vital capacity and forced expiratory volume in 1 s/forced vital capacity by Global Sleep Assessment Questionnaire responses adjusted for confounders. The same models were employed to examine respiratory symptoms, as reported on the St George's Respiratory Questionnaire and Chronic Obstructive Pulmonary Disease Assessment Test, by Global Sleep Assessment Questionnaire responses. Logistic regression models were used to assess the association of undiagnosed obstructive airway disease with sleep symptoms. Amongst 2093 adults included in the study, 48.3% were female and the median age was 63 years (interquartile range 53-72). Two-hundred and five (9.79%) subjects met spirometry criteria for undiagnosed chronic obstructive pulmonary disease, and 191 (9.13%) for undiagnosed asthma. There were no significant associations between spirometry measures and sleep symptoms (p > 0.5), controlling for age, sex, body mass index, smoking and comorbidities. Those with undiagnosed asthma were more likely to report insomnia "at least sometimes" versus "never" (odds ratio 2.58, 95% confidence interval: 1.27-6.19, p = 0.02). Respiratory symptoms were associated with sleep symptoms, with significant (p < 0.05) increases in St George's Respiratory Questionnaire and Chronic Obstructive Pulmonary Disease Assessment Test scores in those reporting most sleep symptoms. Overall, we found an association between undiagnosed asthma and insomnia, and between respiratory and sleep disorder symptoms.

Indexed as

AsthmaPulmonary Disease, Chronic ObstructiveSleep Wake DisordersAgedCross-Sectional StudiesFemaleForced Expiratory VolumeHumansMaleMiddle AgedProspective StudiesSpirometrySurveys and QuestionnairesVital Capacityobstructive airway diseaserespiratory symptomssleep disordersspirometry

Identifiers

PMID39322312
PMCPMC12069759

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.