Evidence map›Paper›PMID 39322263›Full record

ReviewEuropean respiratory review : an official journal of the European Respiratory Society2024

Bronchiectasis in Asia: a review of current status and challenges.

Hayoung Choi, Jin-Fu Xu, Sanjay H Chotirmall, James D Chalmers, Lucy C Morgan, Raja Dhar

Registry-linked trialAbstract readReview
In one paragraph

Review in European respiratory review : an official journal of the European Respiratory Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07088926 (A Phase IIb Randomized, Double-blind, Placebo-controlled, Parallel, Multidose Study to Evaluate the Efficacy, Safety, and PK of AZD0292 in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07088926 phase2recruitingnot on this mapstarted 2025, after this paper: background citation

A Phase IIb Randomized, Double-blind, Placebo-controlled, Parallel, Multidose Study to Evaluate the Efficacy, Safety, and PK of AZD0292 in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization

TypeinterventionalSponsorAstraZenecaRan2025 to 2028Enrolled435ConditionsBronchiectasis With Pseudomonas Aeruginosa ColonizationArmsAZD0292, Placebo
3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Non-cystic fibrosis bronchiectasis in Taiwan.BMJ open respiratory research · 2025
    Observational
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hayoung ChoiDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0003-4812-0653
Jin-Fu XuDepartment of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Sanjay H ChotirmallLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.ORCID https://orcid.org/0000-0003-0417-7607
James D ChalmersDivision of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.
Lucy C MorganDepartment of Respiratory Medicine Concord Hospital, Concord Clinical School University of Syndey, Sydney, Australia.ORCID https://orcid.org/0000-0001-6389-1953
Raja DharDepartment of Pulmonology, CK Birla Group of Hospitals, Kolkata, India docaardee@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent bronchiectasis studies from large-scale multinational, multicentre registries have demonstrated that the characteristics of the disease vary according to geographic region. However, most perspectives on bronchiectasis are dominated by data from Western countries. This review intends to provide an Asian perspective on the disease, focusing on the established registries in India, Korea and China. Asian patients with bronchiectasis are less likely to show female predominance and experience exacerbations, are more likely to be younger, have milder disease, and have fewer options for guideline-recommended treatment than those living in other global regions. Furthermore, Asian bronchiectasis patients demonstrate different comorbidities, microbiological profiles and unique endophenotypes, including post-tuberculosis and dry bronchiectasis. Notably, each Asian region reveals further geographic variations and inter-patient differences. Future studies are warranted to better characterise Asian patients with bronchiectasis.

Indexed as

BronchiectasisAsiaAsian PeopleComorbidityDisease ProgressionFemaleHealth Status DisparitiesHumansLungMalePrevalencePrognosisRisk Factors

Identifiers

PMID39322263
PMCPMC11423131

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.