ArticleImmunology1985
Eosinophil adherence to infective larvae of Trichinella spiralis: quantification and modulation.
Article in Immunology, 1985. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
0 citing papers in PubMed, 3 citations in OpenAlex.
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Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Eosinophils play an important role in host defence against helminthic infection. A quantitative system for studying the interactions of eosinophils and a large non-ingestible target was developed using infective muscle-stage larvae of Trichinella spiralis. At 37 degrees, this antibody-dependent system provided a reliable, reproducible index of eosinophil function. Adherence was equivalent under aerobic and anaerobic conditions. No significant differences were noted between peritoneal exudate eosinophils from Trichinella-infected and normal animals. Adherence was inhibited by leukotriene inhibitors [eicosaetraynoic acid (10(-3) M), nordihydroguaiaretic acid (10(-4) M), and BW755C (10(-3) M)] but not by prostaglandin inhibitors (aspirin and indomethacin), suggesting that leukotrienes mediate this eosinophil function. This assay provides another useful method for assessment of a crucial eosinophil function.
Indexed as
Identifiers
3932192PMC1453700W144063102What OpenQuestion holds
Registered trials
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