Evidence map›Paper›PMID 39321279›Full record

Observational studyEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery2024

An analysis of early and long-term gender-related outcomes after thoracic endovascular aortic repair.

Gabriele Piffaretti, Francesca Mauri, Gaddiel Mozzetta, Sergio Zacà, Raffaele Pulli, Giovanni Pratesi, Aaron Thomas Fargion, Domenico Angiletta, I.C.E., Italian Collaborators for Thoracic Evar Registry

Abstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Gabriele PiffarettiVascular Surgery, Department of Medicine and Surgery, University of Insubria School of Medicine, 21100 Varese, Italy.ORCID 0000-0002-9906-4658
Francesca MauriVascular Surgery, Department of Medicine and Surgery, University of Insubria School of Medicine, 21100 Varese, Italy.
Gaddiel MozzettaVascular Surgery, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa School of Medicine, 16132 Genoa, Italy.
Sergio ZacàVascular Surgery, Department of Emergency and Organs Transplantation, University of Bari School of Medicine, 70124 Bari, Italy.
Raffaele PulliVascular Surgery, Department of Cardiothoracic and Vascular Surgery, University of Florence School of Medicine, 50134 Florence, Italy.
Giovanni PratesiVascular Surgery, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa School of Medicine, 16132 Genoa, Italy.
Aaron Thomas FargionVascular Surgery, Department of Cardiothoracic and Vascular Surgery, University of Florence School of Medicine, 50134 Florence, Italy.
Domenico AngilettaVascular Surgery, Department of Emergency and Organs Transplantation, University of Bari School of Medicine, 70124 Bari, Italy.
I.C.E., Italian Collaborators for Thoracic Evar Registry

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate gender-related outcomes during endovascular treatment of thoracic and thoraco-abdominal aortic diseases (TEVAR).

methodsMulticentre, retrospective, observational cohort study. All TEVARs between January 2005 and April 2023 were identified. Primary outcomes were 30-day mortality and cumulative survival. Secondary outcomes were vascular access complications, and freedom from TEVAR-related reintervention. Interventions performed in male patients were matched to females on the basis of a one-to-one coarsened exact matching.

resultsWe identified 151 males who were matched with 151 females. Mortality at 30 days was not statistically different between females and males (11.2% vs 11.2%; P = 1.0). At binary logistic regression analysis, duration of intervention (P = 0.001) and emergency TEVAR (P = 0.001) were associated with mortality at 30 days. Gender did not impact the access vessel complication rate [n = 6 (4.0%) vs n = 5 (3.3%); P = 1.0]. The median follow-up was 46 (interquartile range, 7-84) months with no difference between males and females [median 50 (11-95) vs 37.5 (3.5-71.2); P = 0.153]. Estimated survival was not statistically different between females and males [log-rank χ2 = 0.6, P = 0.442; 95% confidence interval (CI) 110.7-207.3]. At Cox's regression analysis, gender did not impact overall survival (hazard ratio 0.8; 95% CI 0.6-1.3; P = 0.450). Estimated freedom from TEVAR-related reinterventions was not statistically different between females and males (log-rank χ2 = 0.4, P = 0.837; 95% CI 187.8-219.3).

conclusionsFemale gender itself was not associated with worse 30-day mortality and late survival than males with similar access vessel complication as well as TEVAR-related reintervention rate.

Indexed as

Aorta, ThoracicEndovascular ProceduresAgedAortic DiseasesBlood Vessel Prosthesis ImplantationEndovascular Aneurysm RepairFemaleHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesSex FactorsTime FactorsTreatment OutcomeAccess complicationAorta-related mortalityFemale genderFreedom from reinterventionThoracic endovascular aortic repair

Identifiers

PMID39321279
PMCPMC12017470

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.