ArticleEndocrine2025
Symptom clusters of patients with advanced thyroid cancer: a cross-sectional study.
Article in Endocrine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Symptom clusters and quality of life among patients with thyroid cancer during early survivorship: a national multicenter cross-sectional study.The oncologist · 2026Article
- Symptom clusters and contemporaneous symptom network analysis at discharge in patients with differentiated thyroid cancer after thyroidectomy.Endocrine · 2026Article
- Perioperative symptoms in patients with thyroid cancer: a cross-sectional and longitudinal network analysis.BMC endocrine disorders · 2025Observational
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2 authors.
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Abstract
purposeTo investigate and analyze the symptom clusters of patients with advanced thyroid cancer and provide a basis for developing targeted symptom management measures.
methodsPatients who visited a multidisciplinary outpatient service for advanced thyroid cancer at a tertiary A hospital in Sichuan Province from April 2022 to April 2023 were selected using convenience sampling. A cross-sectional survey was conducted using the M.D. Anderson Symptom Inventory-Thyroid Cancer module (MDASI-THY). Symptom clusters were extracted by exploratory factor analysis.
resultsDisturbed sleep had the highest incidence (75.7%) and severity (3.0 points), while mood distress had the highest incidence (63.5%) and severity (2.0 points) of symptom interference. Three symptom clusters were identified: mood-fatigue-sleep, digestive tract-sensation, and thyroid cancer-specific symptom clusters.
conclusionPatients with advanced thyroid cancer have multiple symptom clusters that seriously affect their daily lives. Health care professionals should conduct targeted observation and preventive treatment to reduce the burden of symptoms on patients.
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