Evidence map›Paper›PMID 39319525›Full record

ArticleHistology and histopathology2025

Periostin acts as an oncogene to promote laryngeal cancer progression by activating decorin.

Chao Wu, Bo Yang, Jiusheng Chu

Abstract read
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In one paragraph

Article in Histology and histopathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chao WuDepartment of Otolaryngology Head and Neck Surgery, Taizhou People's Hospital, Taizhou, Jiangsu Province, China. doctorwu521@126.com.
Bo YangDepartment of Otolaryngology Head and Neck Surgery, Taizhou People's Hospital, Taizhou, Jiangsu Province, China.
Jiusheng ChuDepartment of Otolaryngology Head and Neck Surgery, Taizhou People's Hospital, Taizhou, Jiangsu Province, China.

Funding

Science and Technology Development Project of Taizhou People's Hospital ZL202038
6 · The paper itself

Abstract

Laryngeal carcinoma (LC) is the second most common malignancy of the head and neck worldwide, with increasing incidence every year. However, the mechanism of its development is not completely clear. Periostin (POSTN) has been reported to be involved in various aspects of tumorigenesis. To determine the influence of POSTN on LC tumorigenesis, we first examined the expression of POSTN in tissues from patients with LC through immunohistochemistry, western blot, and qRT-PCR. Besides, we demonstrated that POSTN promoted LC cell migration, invasion, and proliferation

Indexed as

Cell Adhesion MoleculesDecorinLaryngeal NeoplasmsAnimalsCell Line, TumorCell MovementCell ProliferationDisease ProgressionFemaleGene Expression Regulation, NeoplasticHumansMaleMiceMice, NudeMiddle AgedOncogenesCell Adhesion MoleculesDCN protein, humanDecorinPeriostinPOSTN protein, human

Identifiers

PMID39319525

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.