Evidence map›Paper›PMID 39319361›Full record

Observational studyMediators of inflammation2024

LIPS and PaO

Ziyuan Shen, Zhongnan Yin, Senhao Wei, Zhukai Cong, Feng Zhao, Hua Zhang, Xi Zhu

Abstract readObservational Study
In one paragraph

Observational study in Mediators of inflammation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ziyuan ShenDepartment of Critical Care Medicine Peking University Third Hospital, Beijing 100191, China.
Zhongnan YinBiobank Peking University Third Hospital, Beijing 100191, China.
Senhao WeiDepartment of Critical Care Medicine Peking University Third Hospital, Beijing 100191, China.
Zhukai CongDepartment of Critical Care Medicine Peking University Third Hospital, Beijing 100191, China.
Feng ZhaoDepartment of Critical Care Medicine Peking University Third Hospital, Beijing 100191, China.
Hua ZhangCenter of Epidemiology Peking University Third Hospital, Beijing 100191, China.ORCID https://orcid.org/0000-0002-9103-4796
Xi ZhuDepartment of Critical Care Medicine Peking University Third Hospital, Beijing 100191, China.ORCID https://orcid.org/0009-0007-9461-4124

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore and validate the value of clinical parameters combined with plasma biomarkers for predicting acute respiratory distress syndrome (ARDS) in patients of high risks in the surgical intensive care unit (SICU). Materials and Methods: We conducted a prospective, observational study from January 2020 to December 2023, which enrolled 263 patients of high risks in the SICU of Peking University Third Hospital consecutively; they were classified as ARDS and non-ARDS according to whether ARDS occurred after enrollment. Collected clinical characteristics and blood samples within 24 hr of admission to SICU. Blood samples from the first day to the seventh day of SICU were collected from patients without ARDS, and patients with ARDS were collected until 1 day after ARDS onset, forming data based on time series. ELISA and CBA were used to measure plasma biomarkers. Endpoint of the study was the onset of ARDS. Cox proportional hazard regression analysis was used to find independent risk factors of the onset of ARDS, then constructed a nomogram and tested its goodness-of-fit. Results: About 84 of 263 patients ended with ARDS. Univariate analysis found 15 risk factors showed differences between ARDS and non-ARDS, namely, interleukin 6, interleukin 8 (IL-8), angiopoietin Ⅱ, LIPS, APACHEⅡ, SOFA, PaO Conclusions: LIPS, PaO

Indexed as

BiomarkersIntensive Care UnitsRespiratory Distress SyndromeAdultAgedAngiopoietin-2FemaleHumansInterleukin-6Interleukin-8MaleMiddle AgedProportional Hazards ModelsProspective StudiesReceptor for Advanced Glycation End ProductsRisk FactorsAngiopoietin-2BiomarkersInterleukin-6Interleukin-8Receptor for Advanced Glycation End Products

Identifiers

PMID39319361
PMCPMC11421942

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.