Evidence map›Paper›PMID 39319074›Full record

ArticleIndustrial & engineering chemistry research2024

β-Lactoglobulin Enhances Clay and Activated Carbon Binding and Protection Properties for Cadmium and Lead.

Kendall Lilly, Meichen Wang, Asuka A Orr, Sarah E Bondos, Timothy D Phillips, Phanourios Tamamis

Abstract read
In one paragraph

Article in Industrial & engineering chemistry research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kendall LillyDepartment of Materials Science and Engineering, College of Engineering, Texas A&M University, College Station, Texas 77843, United States.
Meichen WangDepartment of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas 77843, United States.
Asuka A OrrArtie McFerrin Department of Chemical Engineering, College of Engineering, Texas A&M University, College Station, Texas 77843, United States.ORCID https://orcid.org/0000-0003-4628-526X
Sarah E BondosDepartment of Medical Physiology Texas A&M Health Science Center, Texas A&M University, College Station, Texas 77843, United States.ORCID https://orcid.org/0000-0002-9673-4169
Timothy D PhillipsDepartment of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas 77843, United States.ORCID https://orcid.org/0000-0003-1823-5716
Phanourios TamamisDepartment of Materials Science and Engineering, College of Engineering, Texas A&M University, College Station, Texas 77843, United States.ORCID https://orcid.org/0000-0002-3342-2651

Funding

Single cell, multi-parametric high throughput platform to classify endocrine disruptor potential of mixturesP42ES027704 · NIEHS · TEXAS A&M UNIVERSITY · PI Thomas Joseph McDonald · 2017 to 2026
$21.2M
Development of edible sorbent therapies to mitigate dietary exposures to per- and polyfluoroalkyl substances (PFAS)R00ES034090 · NIEHS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI WANG, MEICHEN · 2024 to 2025
$730k
Development of edible sorbent therapies to mitigate dietary exposures to per- and polyfluoroalkyl substances (PFAS)K99ES034090 · NIEHS · TEXAS A&M AGRILIFE RESEARCH · PI WANG, MEICHEN · 2023 to 2024
$154k
NIEHS NIH HHS K99 ES034090NIEHS NIH HHS P42 ES027704NIEHS NIH HHS R00 ES034090
6 · The paper itself

Abstract

The removal of heavy metals from wastewater remains a challenge due to the limitations of current remediation methods. This study aims to develop multicomponent composites as inexpensive and environmentally friendly sorbents with enhanced capture of cadmium (Cd) and lead (Pb). The composites are based on calcium montmorillonite (CM) and activated carbon (AC) because of their proven effectiveness as sorbents for diverse toxins in environmental settings. In this study, we used a combination of computational and experimental methods to delineate that β-lactoglobulin enhances CM and AC binding and protection properties for Cd and Pb. Modeling and molecular dynamics simulations investigated the formation of material systems formed by CM and AC in complex with β-lactoglobulin and predicted their capacity to bind heavy metal ions at neutral pH conditions. Our simulations suggest that the enhanced binding properties of the material systems are attributed to the presence of several binding pockets formed by β-lactoglobulin for the two heavy metal ions. At neutral pH conditions, divalent Cd and Pb shared comparable binding propensities in all material systems, with the former being consistently higher than the latter. To validate the interactions depicted in simulations, two ecotoxicological models (

Identifiers

PMID39319074
PMCPMC11417999

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.