Evidence map›Paper›PMID 39319036›Full record

ArticleInfection and drug resistance2024

Bacterial Epidemiology and Antimicrobial Resistance Profiles of Bloodstream Infections Caused by Negative Bacteria in Children's: A Multicenter Study in China (2016-2022).

Hongmei Xu, Ningning Wu, Hui Yu, Chuanqing Wang, Jikui Deng, Hongmei Wang, Chunzhen Hua, Yinghu Chen, Xuejun Chen, Ting Zhang and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and drug resistance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Hongmei XuInfectious Disease Department, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; Chongqing Key Laboratory of Child Rare Diseases in Infection and Immunity, Chongqing, People's Republic of China.
Ningning WuDepartment of Clinical Laboratory, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; Chongqing Key Laboratory of Child Rare Diseases in Infection and Immunity, Chongqing, People's Republic of China.
Hui YuInfectious Disease Department, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, People's Republic of China.
Chuanqing WangDepartment of Clinical Microbiology Laboratory, Nosocomial Infection Control Department, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, People's Republic of China.
Jikui DengInfectious Disease Department, Shenzhen Children's Hospital, Shenzhen, People's Republic of China.
Hongmei WangInfectious Disease Department, Shenzhen Children's Hospital, Shenzhen, People's Republic of China.
Chunzhen HuaInfectious Disease Department, Children's Hospital of Zhejiang University, Zhejiang, People's Republic of China.
Yinghu ChenInfectious Disease Department, Children's Hospital of Zhejiang University, Zhejiang, People's Republic of China.
Xuejun ChenDepartment of Medical Laboratory, Children's Hospital of Zhejiang University, Zhenjiang, People's Republic of China.
Ting ZhangDigestive and Infectious Disease Department, Children's Hospital of Shanghai Jiaotong University, Shanghai, People's Republic of China.
Hong ZhangDepartment of Medical Laboratory, Children's Hospital of Shanghai Jiaotong University, Shanghai, People's Republic of China.
Yiping ChenPediatric Infectious Disease Department, Second Affiliated Hospital, and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Shifu WangDepartment of Medical Laboratory, Qilu Children's Hospital, Shandong University, Shandong, People's Republic of China.ORCID 0000-0002-2131-9518
Qing CaoInfectious Disease Department, Shanghai Children's Medical Center, Shanghai, People's Republic of China.
Huiling DengInfectious Disease Department, Xi'an Children's Hospital, Xi'an, People's Republic of China.
Sancheng CaoDepartment of Medical Laboratory, Xi'an Children's Hospital, Xi'an, People's Republic of China.
Jianhua HaoInfectious Disease Department, Children's Hospital of Kaifeng City, Kaifeng, People's Republic of China.
Wei GaoDepartment of Medical Laboratory, Children's Hospital of Kaifeng City, Kaifeng, People's Republic of China.
Chunmei JingDepartment of Clinical Laboratory, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; Chongqing Key Laboratory of Child Rare Diseases in Infection and Immunity, Chongqing, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Aim to investigate the pathogens distribution and drug resistance of gram-negative bacteria causing bloodstream infection (BSIs) in Infectious Disease Surveillance of Pediatric from 2016 to 2022. The prevalence of four important drug resistance phenotypes was studied: difficult-to-treat resistance, fluoroquinolone resistance, carbapenem resistance, and extended-spectrum cephalosporin resistance, and to provide reference basis for preventing and treating BSIs diseases in children. Methods: Strain identification and antimicrobial susceptibility tests were independently performed at each hospital. Data were analyzed using Whonet 5.6 and GraphPad Prism 8 software. The Mann-Whitney Results: A total of 39977 BSIs strains were isolated, with 27.1% of the negative bacteria causing BSIs (10824 strains). The highest bacteria detected were Conclusion: The detection rate of gram-negative pathogens showed an increasing trend among the bloodstream infection. The detection rate of CRKPN assumed a downward trend in 2018. There are differences types of pathogens between the neonatal group and the pediatric group, The detection rate of CRKPN in the neonate group was significantly higher than pediatric group. The first average detection rates for carbapenem resistance, extended-spectrum cephalosporin resistance, and fluoroquinolone resistance were obtained for

Indexed as

bloodstream infectioncarbapenem resistancedifficult-to-treat resistanceextended-spectrum cephalosporin resistancefluoroquinolone resistancepathogenic bacterium

Identifiers

PMID39319036
PMCPMC11421437

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.