Evidence map›Paper›PMID 39318868›Full record

ArticleJGH open : an open access journal of gastroenterology and hepatology2024

Liver transplant recipients have worse metabolic body phenotype compared with matched non-transplant controls.

Chandra Bhati, Danielle Kirkman, Mikael F Forsgren, Hiba Kamal, Hiba Khan, Sherry Boyett, Olof Dahlqvist Leinhard, Jennifer Linge, Vaishali Patel, Samarth Patel and 2 more

Abstract read
In one paragraph

Article in JGH open : an open access journal of gastroenterology and hepatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chandra BhatiDivision of Transplant Surgery University of Maryland Baltimore Maryland USA.
Danielle KirkmanDepartment of Kinesiology and Health Sciences Virginia Commonwealth University (VCU) Richmond Virginia USA.
Mikael F ForsgrenAMRA Medical AB Linköping Sweden.
Hiba KamalDivision of Gastroenterology and Hepatology VCU Richmond Virginia USA.
Hiba KhanDepartment of Internal Medicine VCU Richmond Virginia USA.
Sherry BoyettDivision of Gastroenterology and Hepatology VCU Richmond Virginia USA.
Olof Dahlqvist LeinhardAMRA Medical AB Linköping Sweden.
Jennifer LingeAMRA Medical AB Linköping Sweden.
Vaishali PatelDivision of Gastroenterology and Hepatology VCU Richmond Virginia USA.
Samarth PatelUniversity of Pennsylvania Philadelphia Pennsylvania USA.
Susan WolverDepartment of Internal Medicine VCU Richmond Virginia USA.
Mohammad S SiddiquiDivision of Gastroenterology and Hepatology VCU Richmond Virginia USA.ORCID https://orcid.org/0000-0001-7392-7489

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Quantification of body compartments, particularly the interaction between adipose tissue and skeletal muscle, is emerging as novel a biomarker of metabolic health. The present study evaluated the impact of liver transplant (LT) on body compartments. Methods: Totally 66 adult LT recipients were enrolled in whom body compartments including visceral adipose tissue (VAT), abdominal subcutaneous adipose tissue (ASAT), muscle fat infiltration (MFI), fat-free muscle volume (FFMV), and liver fat (LF) were quantified via whole body magnetic resonance imaging (MRI). To provide non-LT comparison, each LT recipient was matched to at least 150 non-LT controls for same sex, age, and body mass index (BMI) from the UK Biobank registry. Results: LT recipients ( Conclusion: Using non-LT controls, the current study established the higher-than-expected adiposity burden among LT recipients, which is even higher among patients transplanted for MASH cirrhosis. These findings provide data needed to design future studies developing radiomics-based risk-stratification strategies in LT recipients.

Indexed as

body compositionliver transplantationmuscle fat infiltrationskeletal musclevisceral adipose tissuevisceral sarcopenic obesity

Identifiers

PMID39318868
PMCPMC11420625

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.