Evidence map›Paper›PMID 39318628›Full record

ArticleFrontiers in immunology2024

The known and unknown of post-pump chorea: a case report on robust steroid responsiveness implicating occult neuroinflammation.

Muhammad Iqbal, Muizz Zaman, Niranjan Ojha, Yung-Tian A Gau, Eufrosina I Young

Abstract readCase Reports
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Muhammad IqbalDepartment of Neurology, SUNY Upstate Medical University, Syracuse, NY, United States.
Muizz ZamanDepartment of Neurology, SUNY Upstate Medical University, Syracuse, NY, United States.
Niranjan OjhaDepartment of Neurology, SUNY Upstate Medical University, Syracuse, NY, United States.
Yung-Tian A GauDepartment of Neurology, SUNY Upstate Medical University, Syracuse, NY, United States.
Eufrosina I YoungDepartment of Neurology, SUNY Upstate Medical University, Syracuse, NY, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-pump chorea (PPC) is characterized by the development of choreiform movements following cardiopulmonary bypass (CPB) surgery. PPC occurs almost exclusively in children, and its pathophysiology remains unclear. Here we present an adult case of PPC after bovine aortic valve replacement (AVR) which exhibited dramatic and reproducible response to steroid, suggesting the presence of occult neuroinflammation. This observation suggests a novel underlying mechanism in certain subgroups of PPC, which is likely a heterogeneous condition to start with. Further research into the pathomechanisms of PPC could offer insights into managing this otherwise symptomatic control-only condition.

Indexed as

Cardiopulmonary BypassChoreaNeuroinflammatory DiseasesAortic ValveFemaleHeart Valve Prosthesis ImplantationHumansMaleMiddle AgedPostoperative Complicationsbioprosthetic aortic valvecardiopulmonary bypass (CPB)chorea (non-Huntington’s)hypoxia inducible factorneuroinflammationpost-pump chorea

Identifiers

PMID39318628
PMCPMC11419990

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.