Evidence map›Paper›PMID 39317904›Full record

ArticleCurrent microbiology2024

Characterization and Promising in vitro Antiherpetic Effect of Galactomannan from Delonix regia Seeds.

Jonatas Fernando Cavalini de Moraes, Daniele Zendrini Rechenchoski, André Luiz Dyna, Arcelina Pacheco Cunha, Nágila Maria Pontes Silva Ricardo, Silvana Silveira de Farias, Selene Maia de Morais, Lucy Megumi Yamauchi, Ligia Carla Faccin-Galhardi

Abstract read
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In one paragraph

Article in Current microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Anti-HSV-1 agents: an update.Frontiers in pharmacology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jonatas Fernando Cavalini de MoraesDepartamento de Microbiologia, Universidade Estadual de Londrina, Londrina, PR, CEP 86057-970, Brazil.
Daniele Zendrini RechenchoskiDepartamento de Microbiologia, Universidade Estadual de Londrina, Londrina, PR, CEP 86057-970, Brazil.
André Luiz DynaDepartamento de Microbiologia, Universidade Estadual de Londrina, Londrina, PR, CEP 86057-970, Brazil.
Arcelina Pacheco CunhaDepartamento de Química Orgânica E Inorgânica, Universidade Federal Do Ceará, Fortaleza, CE, CEP 60455-760, Brazil.
Nágila Maria Pontes Silva RicardoDepartamento de Química Orgânica E Inorgânica, Universidade Federal Do Ceará, Fortaleza, CE, CEP 60455-760, Brazil.
Silvana Silveira de FariasPrograma Rede Nordeste de Biotecnologia, Universidade Federal Do Ceará, Fortaleza, CE, CEP 60455-760, Brazil.
Selene Maia de MoraisPrograma Rede Nordeste de Biotecnologia, Universidade Federal Do Ceará, Fortaleza, CE, CEP 60455-760, Brazil.
Lucy Megumi YamauchiDepartamento de Microbiologia, Universidade Estadual de Londrina, Londrina, PR, CEP 86057-970, Brazil.
Ligia Carla Faccin-GalhardiDepartamento de Microbiologia, Universidade Estadual de Londrina, Londrina, PR, CEP 86057-970, Brazil. lgalhardi@uel.br.ORCID http://orcid.org/0000-0002-7522-9710

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 304248/2022-3
6 · The paper itself

Abstract

Herpes simplex virus (HSV) infections can occur throughout life, thereby allowing transmission to new hosts, with an impact on public health. Acyclovir remains the treatment of choice for these infections; however, an increase in resistant strains in recent years has been observed. In this study, the activity of a native Delonix regia galactomannan (NDr) against HSV-1 was investigated in vitro. NDr was characterized using infrared spectroscopy and NMR. Evaluation of cytotoxicity and the antiviral effect was determined, respectively, by MTT and plaque reduction assays. The NDr concentrations that inhibited cell viability (CC

Indexed as

Antiviral AgentsGalactoseHerpesvirus 1, HumanMannansSeedsAnimalsCell SurvivalChlorocebus aethiopsHerpes SimplexHumansPlant ExtractsVero CellsVirus ReplicationAntiviral AgentsgalactomannanGalactoseMannansPlant Extracts

Identifiers

PMID39317904

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.