ArticleAesthetic plastic surgery2025
Clinical Experience in the Management of the Polyacrylamide Hydrogel (PAAG) Associated Complications Including Four Breast Cancer Cases: A Retrospective Study of 135 Cases.
Article in Aesthetic plastic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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Who cites it
4 citing papers in PubMed.
- Article
- Case Report: Ulcerative breast cancer occurring 20 years after breast augmentation with Amazingel injection.Frontiers in oncology · 2026Article
- Multiple bilateral breast hematomas as a complication of polyacrylamide hydrogel injection for breast augmentation: A case report.JPRAS open · 2025Article
- Applications of Hydrogels in Emergency Therapy.Gels (Basel, Switzerland) · 2025Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundComplications often arose after polyacrylamide hydrogel (PAAG) injections for breast augmentation. This study aimed to explore the complications and clinical management of breast augmentation with PAAG.
methodsWe retrospectively analyzed the data of 135 patients who underwent breast PAAG removal from January 2011 to December 2023 in our hospital. We also comprehensively analyzed the postoperative clinical results, subsequent complications, and clinical management after PAAG injections.
resultsInduration and nodules (60.0%), pain (27.4%), anxiety (22.2%), migration (13.3%), asymmetry (8.1%), swelling (5.9%), infection (5.2%), calcification (3.7%), and breast cancer (BC) (3.0%) were a few complications after PAAG injections. Although breast cancer was a rare complication, it might be covered up by PAAG tissue. Eighty-eight patients had undergone PAAG removal, while 47 patients had additional breast reconstruction surgery. The post-surgical complications included PAAG residue (17.0%), skin laxity (7.4%), hemorrhage (2.2%), reoperation (1.5%), and nipple or breast asymmetry (1.5%). Additionally, the BREAST-Q scores revealed that patients with breast reconstruction had a significant better outcomes in psychosocial well-being (p < 0.001), satisfaction with breasts (p < 0.001), and sexual well-being (p = 0.008).
conclusionMultiple complications could occur after PAAG injections for breast augmentation. Although rare, BC might need more clinical attention. PAAG removal could alleviate some complications, and breast reconstruction contributed to improved patient satisfaction, psychosocial well-being, and sexual well-being. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
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Registered trials
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