Evidence map›Paper›PMID 39317773›Full record

ArticleNature microbiology2024

Pathogen genomic surveillance status among lower resource settings in Asia.

Marya Getchell, Suci Wulandari, Ruklanthi de Alwis, Shreya Agoramurthy, Yoong Khean Khoo, Tze-Minn Mak, La Moe, Anne-Claire Stona, Junxiong Pang, Muhd Haziq Fikry Haji Abdul Momin and 36 more

Erratum issuedAbstract read
In one paragraph

Article in Nature microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Global Genomic Surveillance.Methods in molecular biology (Clifton, N.J.) · 2027
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

46 authors.

Marya Getchell *Programme in Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore.ORCID http://orcid.org/0000-0002-5831-4008
Suci Wulandari *Centre for Outbreak Preparedness, Duke-NUS Medical School, Singapore, Singapore.
Ruklanthi de AlwisCentre for Outbreak Preparedness, Duke-NUS Medical School, Singapore, Singapore. rukie.dealwis@duke-nus.edu.sg.ORCID http://orcid.org/0000-0002-2319-3701
Shreya AgoramurthyCentre for Outbreak Preparedness, Duke-NUS Medical School, Singapore, Singapore.
Yoong Khean KhooCentre for Outbreak Preparedness, Duke-NUS Medical School, Singapore, Singapore.
Tze-Minn MakBioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
La MoeCentre for Outbreak Preparedness, Duke-NUS Medical School, Singapore, Singapore.ORCID http://orcid.org/0009-0009-5923-2125
Anne-Claire StonaCentre for Outbreak Preparedness, Duke-NUS Medical School, Singapore, Singapore.
Junxiong PangCentre for Outbreak Preparedness, Duke-NUS Medical School, Singapore, Singapore.
Muhd Haziq Fikry Haji Abdul MominDepartment of Laboratory Services, Ministry of Health, Bandar Seri Begawan, Brunei.
Afreenish AmirNational Institute of Health (NIH), Islamabad, Pakistan.
Lucia Rizka AndaluciaDirectorate of Pharmacy and Medical Devices, Ministry of Health, Jakarta, Indonesia.
Ghows AzzamMalaysia Genome and Vaccine Institute (MGVI), Selangor, Malaysia.
Savuth ChinNational Institute of Public Health, Phnom Penh, Cambodia.
Thanat ChookajornMahidol University, Nakhon Pathom, Thailand.
Govindakarnavar ArunkumarWorld Health Organisation country office for Nepal, Kathmandu, Nepal.
Do Thai HungPasteur Institute, Nha Trang, Vietnam.
Aamer IkramNational Institute of Health (NIH), Islamabad, Pakistan.
Runa JhaNational Public Health Laboratory, Kathmandu, Nepal.
Erik A KarlssonInstitut Pasteur du Cambodge (IPC), Phnom Penh, Cambodia.ORCID http://orcid.org/0000-0001-6004-5671
Mai Quynh Le ThiNational Institute of Hygien and Epidemiology (NIHE), Nha Trang, Vietnam.
Surakameth MahasirimongkolDepartment of Medical Sciences, Medical Life Science Institute, Bangkok, Thailand.
Gathsaurie Neelika MalavigeUniversity of Sri Jayewardenepura, Nugegoda, Sri Lanka.
Jessica E ManningNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Phnom Penh, Cambodia.
Syarifah Liza MuniraHealth Policy Agency, Ministry of Health, Jakarta, Indonesia.
Nguyen Vu TrungPasteur Institute, Ho Chi Minh City, Vietnam.
Imran NisarAga Khan University, Karachi, Pakistan.
Firdausi QadriInternational Centre for Diarrhoeal Disease Research (icddr,b), Dhaka, Bangladesh.ORCID http://orcid.org/0000-0002-8928-9888
Farah Naz QamarAga Khan University, Karachi, Pakistan.
Matthew T RobinsonLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital, Quai Fa Ngum, Vientiane, Laos.ORCID http://orcid.org/0000-0003-1187-2712
Cynthia P SalomaPhilippine Genome Center, University of the Philippines, Luzon, Philippines.ORCID http://orcid.org/0000-0002-3351-3465
Swe SetkNational Health Laboratory, Department of Medical Service, Ministry of Health, Yangon, Myanmar.
Tahmina ShirinInstitute of Epidemiology, Disease Control and Research (IEDCR), Dhaka, Bangladesh.
Le Van TanOxford University Clinical Research Unit (OUCRU), Ho Chi Minh City, Vietnam.
Timothy John R DizonResearch Institute for Tropical Medicine (RITM), Quezon, Philippines.
Ravindran ThayanInstitute for Medical Research, Selangor, Malaysia.
Hlaing Myat ThuDepartment of Medical Research, Ministry of Health, Yangon, Myanmar.
Hasitha TisseraMinistry of Health, Colombo, Sri Lanka.
Phonepadith XangsayarathNational Centre for Laboratory and Epidemiology (NCLE), Vientiane, Laos.
Zainun ZainiDepartment of Laboratory Services, Ministry of Health, Bandar Seri Begawan, Brunei.
John C W LimSingHealth Duke-NUS Global Health Institute, Singapore, Singapore.
Sebastian Maurer-StrohBioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID http://orcid.org/0000-0003-0813-9640
Gavin J D SmithCentre for Outbreak Preparedness, Duke-NUS Medical School, Singapore, Singapore.ORCID http://orcid.org/0000-0001-5031-468X
Lin-Fa WangProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.ORCID http://orcid.org/0000-0003-2752-0535
Paul PronykCentre for Outbreak Preparedness, Duke-NUS Medical School, Singapore, Singapore.
Asia Pathogen Genomics Initiative (Asia PGI) consortium

Funding

Wellcome TrustWellcome Trust (Wellcome) 315753/Z/24/ZWorld Health Organization 001
6 · The paper itself

Abstract

Asia remains vulnerable to new and emerging infectious diseases. Understanding how to improve next generation sequencing (NGS) use in pathogen surveillance is an urgent priority for regional health security. Here we developed a pathogen genomic surveillance assessment framework to assess capacity in low-resource settings in South and Southeast Asia. Data collected between June 2022 and March 2023 from 42 institutions in 13 countries showed pathogen genomics capacity exists, but use is limited and under-resourced. All countries had NGS capacity and seven countries had strategic plans integrating pathogen genomics into wider surveillance efforts. Several pathogens were prioritized for human surveillance, but NGS application to environmental and human-animal interface surveillance was limited. Barriers to NGS implementation include reliance on external funding, supply chain challenges, trained personnel shortages and limited quality assurance mechanisms. Coordinated efforts are required to support national planning, address capacity gaps, enhance quality assurance and facilitate data sharing for decision making.

Indexed as

GenomicsHigh-Throughput Nucleotide SequencingAnimalsAsiaCommunicable DiseasesEpidemiological MonitoringHumans

Identifiers

PMID39317773
PMCPMC11445059

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.