Evidence map›Paper›PMID 39317345›Full record

ArticleVirulence2024

Association of hepatitis B core antibody level and hepatitis B surface antigen clearance in HBeAg-negative patients with chronic hepatitis B.

Jian Wang, Zhiyi Zhang, Li Zhu, Qing Zhang, Shaoqiu Zhang, Yifan Pan, Jiacheng Liu, Fei Cao, Tao Fan, Ye Xiong and 8 more

Abstract read
In one paragraph

Article in Virulence, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Jian WangDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, China.
Zhiyi ZhangDepartment of Infectious Diseases, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Li ZhuDepartment of Infectious Diseases, The Affiliated Infectious Diseases Hospital of Soochow University, Suzhou, Jiangsu, China.
Qing ZhangDepartment of Infectious Diseases, Huai'an No. 4 People's Hospital, Huai'an, Jiangsu, China.
Shaoqiu ZhangDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, China.
Yifan PanDepartment of Infectious Diseases, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, Jiangsu, China.
Jiacheng LiuDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, China.
Fei CaoDepartment of Infectious Diseases, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Tao FanDepartment of Infectious Diseases, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Ye XiongDepartment of Infectious Diseases, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Shengxia YinDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, China.
Xiaomin YanDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, China.
Yuxin ChenInstitute of Viruses and Infectious Diseases, Nanjing University, Nanjing, Jiangsu, China.
Chuanwu ZhuDepartment of Infectious Diseases, The Affiliated Infectious Diseases Hospital of Soochow University, Suzhou, Jiangsu, China.
Jie LiDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, China.
Xingxiang LiuDepartment of Clinical Laboratory, Huai'an No. 4 People's Hospital, Huai'an, Jiangsu, China.
Chao WuDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, China.ORCID 0000-0002-1657-010X
Rui HuangDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, China.ORCID 0000-0002-3189-7960

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Predicting hepatitis B surface antigen (HBsAg) clearance is important for chronic hepatitis B (CHB) patients receiving pegylated interferon-alfa (Peg-IFN) therapy. We aimed to determine the predictive value of serum hepatitis B core antibody (anti-HBc) for HBsAg clearance. A total of 189 HBeAg-negative CHB patients who received Peg-IFN based therapy were retrospectively included and classified into two groups: nucleos(t)ide analogues (NAs) add-on Peg-IFN group (add-on group,

Indexed as

Antiviral AgentsHepatitis B AntibodiesHepatitis B, ChronicHepatitis B e AntigensHepatitis B Surface AntigensInterferon-alphaAdultDrug Therapy, CombinationFemaleHepatitis B Core AntigensHepatitis B virusHumansMaleMiddle AgedPolyethylene GlycolsRecombinant ProteinsAntiviral AgentsHepatitis B AntibodiesHepatitis B Core AntigensHepatitis B e AntigensHepatitis B Surface AntigensInterferon-alphaPolyethylene GlycolsRecombinant Proteinsantiviralfunctional cureHepatitis B surface antigenlevel of anti-HBc antibodypegylated interferon

Identifiers

PMID39317345
PMCPMC11423664

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.