Evidence map›Paper›PMID 39317215›Full record

ArticleAmerican journal of perinatology2025

Hereditary Hemorrhagic Telangiectasia: Pregnancy and Delivery-Specific Considerations and Outcomes.

Virginia Y Watkins, Mira L Estin, Amanda M Craig, Sarah K Dotters-Katz, Jerome J Federspiel

Abstract read
In one paragraph

Article in American journal of perinatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Virginia Y WatkinsDepartment of Obstetrics and Gynecology, Duke University Hospital, Durham, North Carolina.ORCID 0000-0002-7398-9425
Mira L EstinDepartment of Obstetrics and Gynecology, Duke University Hospital, Durham, North Carolina.
Amanda M CraigDepartment of Obstetrics and Gynecology, Duke University Hospital, Durham, North Carolina.ORCID 0000-0001-9147-7119
Sarah K Dotters-KatzDepartment of Obstetrics and Gynecology, Duke University Hospital, Durham, North Carolina.
Jerome J FederspielDepartment of Obstetrics and Gynecology, Duke University Hospital, Durham, North Carolina.ORCID 0000-0003-0321-6280

Funding

Duke Women's Reproductive Health Research ScholarsK12HD103083 · NICHD · DUKE UNIVERSITY · PI Cindy Amundsen · 2020 to 2026
$2.2M
Eunice Kennedy Shriver National Institute of Child Health and Human Development K12HD103083NICHD NIH HHS K12 HD103083
6 · The paper itself

Abstract

Prior studies have evaluated maternal outcomes in patients with hereditary hemorrhagic telangiectasia (HHT), yet pregnancy- and delivery-specific data remain limited. This study aims to evaluate pregnancy and delivery outcomes in patients with HHT.This retrospective cohort study used the Nationwide Readmissions Database to identify patients with HHT diagnosis on delivery between 2010 and 2021. The primary outcome was severe maternal morbidity (SMM). Secondary outcomes included nontransfusion SMM, preterm birth, stillbirth, prelabor rupture of membranes or preterm prelabor rupture of membranes, cesarean delivery, respiratory bleeding, cerebrovascular complications, patient disposition, and length of stay. Trends in the prevalence of HHT at delivery were assessed with logistic regression. Logistic regression analyses, adjusting for age, payer, zip code income, hospital size, and teaching status, were also used to produce adjusted relationships between HHT status and outcomes.The cohort of 21,698,861 delivered pregnancies corresponded to a national estimate of 44,325,599. Of those, 612 (national estimate: 1,265; 2.8 per 100,000) had a diagnosis of HHT. A steady rise in the HHT diagnosis rate during pregnancy from 2010 to 2021 (1.7 per 100,000 in 2010, 3.8 per 100,000 in 2021,

Indexed as

Pregnancy OutcomeTelangiectasia, Hereditary HemorrhagicAdultCesarean SectionFemaleHumansLogistic ModelsPregnancyPremature BirthPremature Rupture of Fetal MembranesRetrospective StudiesStillbirthUnited StatesYoung Adult

Identifiers

PMID39317215
PMCPMC11885051

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.