Evidence map›Paper›PMID 39316578›Full record

ReviewPharmaceutical patent analyst2024

3D-printed immediate release solid dosage forms: a patent evaluation of US11622940B2.

Akshay Sharma, Ritu Rathi, Sanchay Sharma, Tanikan Sangnim, Kampanart Huanbutta, Inderbir Singh

Abstract readReview
In one paragraph

Review in Pharmaceutical patent analyst, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Akshay SharmaChitkara College of Pharmacy, Chitkara University, Punjab, India.ORCID 0000-0002-1472-7361
Ritu RathiChitkara College of Pharmacy, Chitkara University, Punjab, India.ORCID 0000-0002-9367-1975
Sanchay SharmaChitkara College of Pharmacy, Chitkara University, Punjab, India.ORCID 0000-0002-6664-2589
Tanikan SangnimFaculty of Pharmaceutical Sciences, Burapha University, Chonburi, 20131, Thailand.ORCID 0000-0002-9332-384X
Kampanart HuanbuttaDepartment of Manufacturing Pharmacy, College of Pharmacy, Rangsit University, Thanyaburi, Thailand.ORCID 0000-0001-8188-153X
Inderbir SinghChitkara College of Pharmacy, Chitkara University, Punjab, India.ORCID 0000-0002-1860-4246

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three-dimensional (3D) printing is one of the most flexible technologies for preparing tablets, offering controlled drug release profiles. The current patent describes the preparation of immediate-release 3D-printed tablets of hydrochlorothiazide to improve disintegration and dissolution profile. The patent involves the preparation of drug-loaded filament via hot-melt extrusion and utilizing the same filaments for printing 3D-printed tablets using fused deposition modeling. The tablets were printed with different shapes and sizes by incorporating channels within the tablet spaces, termed as gaplets. The introduction of channels within the tablet design improves the disintegration and dissolution profile of the drug significantly. The morphological characteristic of 3D-printed tablets was studied by using scanning electron microscopy and revealed the presence of gaplets in the tablets.

Indexed as

Drug LiberationPatents as TopicPrinting, Three-DimensionalTabletsDelayed-Action PreparationsDrug CompoundingHydrochlorothiazideSolubilityDelayed-Action PreparationsHydrochlorothiazideTablets3D printingdrug delivery systemFDMfused filament fabrication (FFF)HMEhydrochlorothiazidetablet

Identifiers

PMID39316578
PMCPMC11449147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.