Evidence map›Paper›PMID 39316559›Full record

SynthesisPloS one2024

Predictors of self-care in patients with cancer treated with oral anticancer agents: A systematic review.

Silvia Ucciero, Federica Lacarbonara, Angela Durante, Francesco Torino, Izabella Uchmanowicz, Ercole Vellone, Marco Di Nitto

Abstract readSystematic Review
In one paragraph

Synthesis in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Observational
  3. Patient symptoms, confidence, and adherence during the first 8 weeks of targeted oral anticancer agent treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Perceptions of oncology healthcare professional providing care to older adults prescribed oral anticancer medications in the United States: A qualitative study.Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2025
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Silvia UccieroDepartment of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.ORCID 0009-0005-1767-7012
Federica LacarbonaraDepartment of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.ORCID 0000-0003-0719-9430
Angela DuranteSchool of Advanced Studies Sant'Anna, Health Science Center, Pisa, Italy.ORCID 0000-0003-1034-5988
Francesco TorinoDepartment of Systems Medicine, Medical Oncology, Tor Vergata University of Rome, Rome, Italy.
Izabella UchmanowiczDepartment of Nursing and Obstetrics, Wroclaw Medical University, Wroclaw, Poland.
Ercole VelloneDepartment of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.ORCID 0000-0003-4673-7473
Marco Di NittoDepartment of Health Sciences, University of Genoa, Genoa, Italy.ORCID 0000-0001-8951-622X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the last two decades, the use of oral anticancer agents (OAAs) has increased in cancer patients. Despite this, patients and their caregivers face some challenging issues (side effects, drug-to-drug interactions, etc.) related to OAA administration. The three dimensions of self-care by Riegel et al., self-care maintenance (i.e., stability of patient condition), self-care monitoring (i.e., detection of side effects), and self-care management (i.e., management of side effects), may be implemented to avoid negative outcomes. However, knowledge of self-care determinants is necessary to recognise people at risk of poor self-care behaviours.

aimsDetermine which are the predictors of self-care maintenance, self-care monitoring and self-care management in patients with cancer taking OAA.

methodsA systematic review with narrative synthesis was conducted. We included studies on adult patients with cancer using any kind of oral anticancer agent and describing a predictor of self-care. The search was performed on PubMed, CINAHL/PsycINFO, and Web of Science.

resultsOf 3,061 records, 45 studies were included in this review. Forty-six predictors organised into 14 categories were identified. In general, all studies focused only on adherence, considered as a self-care maintenance component, and none of them focused on other dimensions of self-care. The predictors of OAA adherence most reported were age, side effects, and socioeconomic factors (e.g., insurance status, and annual income).

conclusionsThis systematic review highlighted the literature gap on the analysis of determinants of self-care behaviours in patients taking OAAs. This element could be a starting point for future research that can provide elements to support the oncology nursing research agenda, aimed at recognising patients at risk of poor self-care.

Indexed as

Antineoplastic AgentsNeoplasmsSelf CareAdministration, OralHumansMedication AdherenceAntineoplastic Agents

Identifiers

PMID39316559
PMCPMC11421779

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.