Evidence map›Paper›PMID 39316356›Full record

ReviewMolecular neurobiology2025

Role of Exercise on Neuropathic Pain in Preclinical Models: Perspectives for Neuroglia.

Chen-Chen Zhu, Yi-Li Zheng, Chan Gong, Bing-Lin Chen, Jia-Bao Guo

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. [Mechanisms of spinal microglia and astrocytes in exercise-induced analgesia].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chen-Chen ZhuThe Second School of Clinical Medical College, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Yi-Li ZhengDepartment of Sport Rehabilitation, Shanghai University of Sport, Shanghai, 200438, China.
Chan GongThe Second School of Clinical Medical College, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Bing-Lin ChenThe Second School of Clinical Medical College, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China. 123.cbl@163.com.
Jia-Bao GuoThe Second School of Clinical Medical College, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China. gloria0913gjb@163.com.ORCID http://orcid.org/0000-0001-8398-2369

Funding

Jiangsu Commission of Health Z2022004Natural Science Foundation of Jiangsu Province BK20210907Xuzhou Medical University D2020056
6 · The paper itself

Abstract

The benefits of exercise on neuropathic pain (NP) have been demonstrated in numerous studies. In recent studies, inflammation, neurotrophins, neurotransmitters, and endogenous opioids are considered as the main mechanisms. However, the role of exercise in alleviating NP remains unclear. Neuroglia, widely distributed in both the central and peripheral nervous systems, perform functions such as support, repair, immune response, and maintenance of normal neuronal activity. A large number of studies have shown that neuroglia play an important role in the occurrence and development of NP, and exercise can alleviate NP by regulating neuroglia. This article reviewed the involvement of neuroglia in the development of NP and their role in the exercise treatment of NP, intending to provide a theoretical basis for the exercise treatment strategy of NP.

Indexed as

ExerciseNeuralgiaNeurogliaPhysical Conditioning, AnimalAnimalsDisease Models, AnimalHumansAstrocytesExerciseIntervention mechanismsMicrogliaNeuropathic pain

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.