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ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2025

CT-scan-guided-irrigated trans-catheter ablation of epicardial accessory pathways in the coronary sinus: safety and feasibility in pediatric patients.

Fabrizio Drago, Francesco Flore, Rita Blandino, Aurelio Secinaro, Ilaria Cazzoli, Cristina Raimondo, Corrado Di Mambro

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Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Pediatric Electrophysiology in 2024: End of the Year Review.The Journal of innovations in cardiac rhythm management · 2025
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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Fabrizio DragoPaediatric Cardiology and Cardiac Arrhythmias Complex Unit, Bambino Gesù Children's Hospital IRCCS, Piazza Sant'Onofrio, 4 00165, Rome, Italy. fabrizio.drago@opbg.net.ORCID http://orcid.org/0000-0003-1888-373X
Francesco FlorePaediatric Cardiology and Cardiac Arrhythmias Complex Unit, Bambino Gesù Children's Hospital IRCCS, Piazza Sant'Onofrio, 4 00165, Rome, Italy.
Rita BlandinoPaediatric Cardiology and Cardiac Arrhythmias Complex Unit, Bambino Gesù Children's Hospital IRCCS, Piazza Sant'Onofrio, 4 00165, Rome, Italy.
Aurelio SecinaroAdvanced Cardiovascular Imaging Unit, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
Ilaria CazzoliPaediatric Cardiology and Cardiac Arrhythmias Complex Unit, Bambino Gesù Children's Hospital IRCCS, Piazza Sant'Onofrio, 4 00165, Rome, Italy.
Cristina RaimondoPaediatric Cardiology and Cardiac Arrhythmias Complex Unit, Bambino Gesù Children's Hospital IRCCS, Piazza Sant'Onofrio, 4 00165, Rome, Italy.
Corrado Di MambroPaediatric Cardiology and Cardiac Arrhythmias Complex Unit, Bambino Gesù Children's Hospital IRCCS, Piazza Sant'Onofrio, 4 00165, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe most common site of epicardial APs is posterior-septal, and ablation from the coronary sinus (CS) or its main tributaries is needed. However, particularly in children, it can carry a considerable risk of complications, such as coronary artery (CA) injury, CS damage, and perforation. This study aims to assess the efficacy and safety of computed tomography (CT)-scan-guided-irrigated trans-catheter (TC) ablation of epicardial APs through the CS in children.

methodsTwenty-four children (19 males; mean age 13.8 ± 2.6) with posterior-septal and left posterior epicardial APs who underwent an endocavitary electrophysiological study (EPS) and TC ablation from the CS were enrolled in this study. All patients underwent a CT scan to visualize the CS and its branches and their proximity to the CAs before the ablation. Clinical, electrophysiological and follow-up data were collected.

resultsAcute success rate was 87.5% (21 out of 24 procedures). No complications occurred. In 16 (66.7%) patients, the ablation site was detected at the proximal CS, in two (8.3%) patients in the mid-proximal CS and in six (25%) in the middle cardiac vein (MCV). Ablation was achieved using an irrigated radiofrequency (RF) catheter in all patients and without the use of fluoroscopy in 20 patients (83.3%). Over a median follow-up of 15.1 months (IQR 2.5-32.3), no recurrences or complications occurred.

conclusionEpicardial posterior-septal and left posterior APs, in the area of CS or MCV, can be definitively eliminated in most children using CT-scan-guided electro-anatomical mapping and transvenous irrigated RF ablation.

Indexed as

Accessory Atrioventricular BundleCatheter AblationCoronary SinusSurgery, Computer-AssistedTomography, X-Ray ComputedAdolescentChildElectrophysiologic Techniques, CardiacFeasibility StudiesFemaleHumansMalePericardiumTherapeutic IrrigationTreatment OutcomeAblationAccessory pathwayChildrenElectrophysiological study

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.