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ArticleHernia : the journal of hernias and abdominal wall surgery2024

Role of sarcopenia in complex abdominal wall surgery: does it increase postoperative complications and mortality?

Ángela Santana Valenciano, Luis Blázquez Hernando, Álvaro Robín Valle de Lersundi, Javier López Monclús, Joaquín Muñoz Rodríguez, Belén Porrero Guerrero, Laura Román García de León, José Manuel Molina Villar, Manuel Medina Pedrique, Javier Blázquez Sánchez and 2 more

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Article in Hernia : the journal of hernias and abdominal wall surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ángela Santana ValencianoGeneral and Digestive Surgery Department, University Hospital Ramón y Cajal, Ctra. de Colmenar Viejo, Km. 9,100, 28034, Madrid, Spain.ORCID 0000-0001-6069-5543
Luis Blázquez HernandoGeneral and Digestive Surgery Department, University Hospital Ramón y Cajal, Ctra. de Colmenar Viejo, Km. 9,100, 28034, Madrid, Spain. la_blazquez@hotmail.com.ORCID 0000-0001-9424-3908
Álvaro Robín Valle de LersundiGeneral and Digestive Surgery Department, University Hospital Henares, Coslada, Spain.ORCID 0000-0002-4129-643X
Javier López MonclúsGeneral and Digestive Surgery Department, University Hospital Puerta de Hierro, Majadahonda, Spain.ORCID 0000-0002-0719-8633
Joaquín Muñoz RodríguezGeneral and Digestive Surgery Department, University Hospital Puerta de Hierro, Majadahonda, Spain.ORCID 0000-0002-7680-8343
Belén Porrero GuerreroGeneral and Digestive Surgery Department, University Hospital Ramón y Cajal, Ctra. de Colmenar Viejo, Km. 9,100, 28034, Madrid, Spain.
Laura Román García de LeónGeneral and Digestive Surgery Department, University Hospital Puerta de Hierro, Majadahonda, Spain.ORCID 0000-0001-8536-4724
José Manuel Molina VillarGeneral and Digestive Surgery Department, University Hospital Ramón y Cajal, Ctra. de Colmenar Viejo, Km. 9,100, 28034, Madrid, Spain.
Manuel Medina PedriqueGeneral and Digestive Surgery Department, University Hospital Henares, Coslada, Spain.ORCID 0000-0002-3188-1213
Javier Blázquez SánchezRadiology Department, University Hospital Ramón y Cajal, Madrid, Spain.
José María Fernández CebriánGeneral and Digestive Surgery Department, University Hospital Ramón y Cajal, Ctra. de Colmenar Viejo, Km. 9,100, 28034, Madrid, Spain.ORCID 0000-0003-2188-5007
Miguel Ángel García UreñaGeneral and Digestive Surgery Department, University Hospital Henares, Coslada, Spain.ORCID 0000-0002-7356-6211

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSarcopenia is defined as the loss of skeletal muscle mass and is associated with an increased risk or morbidity and mortality in complex surgical patient populations. Its role in complex abdominal wall surgery (AWS) is yet to be determined. The aim of this study is to establish if sarcopenia has an impact on postoperative complications, mortality and hernia recurrence.

methodsRetrospective study of patients undergoing elective surgery for complex incisional hernias > 10 cm (W3 of European Hernia Society classification) between 2014-2023. Sarcopenia was stablished as the skeletal muscle index (SMI), measured at L3 transversal section of a preoperative CT-scan. Previously defined literature-based SMI cutoff values were used: men ≤ 52.4 cm

results135 patients undergoing complex AWS were included. Of them, 38 were sarcopenic (28.1%). The median follow-up time was 13 months (IQR 12-25). In total, 11 patients died (8.1%). We found that sarcopenia was associated with a higher risk of mortality [HR 7.494 (95% CI 1.985-28.289); p 0.003]. There were no statistically significant differences in postoperative complications or hernia recurrence between both groups.

conclusionAlthough sarcopenia does not seem to have an influence on hernia recurrence or the development of postoperative complications, whether local or systemic, in our study sarcopenia is associated with a higher risk of mortality after complex abdominal wall surgery. Nonetheless, with the results obtained in our study, we think that prehabilitation programs before complex AWS is advisable.

Indexed as

Incisional HerniaPostoperative ComplicationsSarcopeniaAbdominal WallAgedFemaleHerniorrhaphyHumansMaleMiddle AgedRecurrenceRetrospective StudiesRisk FactorsComplex abdominal wall surgerHerniaSarcopeniaSurgical risk

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.