Evidence map›Paper›PMID 39316300›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2024

Associations between perceived interpersonal support and aggressiveness of care in the last month of life among patients with advanced cancer.

Madeleine M Hardt, Madison K Pavao, Sosi E Korian, Charlotte D LaPlante, Paul K Maciejewski, Holly G Prigerson

Abstract readMulticenter Study
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Madeleine M HardtDepartment of Medicine, Weill Cornell Medicine, 420 E. 70th Street, New York, NY, USA. mah4048@med.cornell.edu.ORCID http://orcid.org/0000-0001-7815-0787
Madison K PavaoCornell Center for Research On End-of-Life Care, 420 E. 70th Street, New York, NY, USA.
Sosi E KorianCornell Center for Research On End-of-Life Care, 420 E. 70th Street, New York, NY, USA.
Charlotte D LaPlanteCornell Center for Research On End-of-Life Care, 420 E. 70th Street, New York, NY, USA.
Paul K MaciejewskiDepartment of Medicine, Weill Cornell Medicine, 420 E. 70th Street, New York, NY, USA.
Holly G PrigersonDepartment of Medicine, Weill Cornell Medicine, 420 E. 70th Street, New York, NY, USA.

Funding

Psychosocial Approaches to Better Understanding & End-Stage Cancer Care (PROTECT)R35CA197730 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Holly Gwen Prigerson · 2015 to 2026
$11.2M
Quality of Death: Ethnic and Psychosocial InfluencesR01CA106370 · NCI · YALE UNIVERSITY · PI PRIGERSON, HOLLY GWEN · 2004 to 2015
$4.1M
The Weill Cornell Medicine Research Training Program in Behavioral GeriatricsT32AG049666 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI SARA J CZAJA, Manney Carrington Reid · 2016 to 2026
$3.2M
A Multisite Randomized Controlled Trial of EMPOWER for Family Surrogates of Critically Ill PatientsR01NR019831 · NINR · WEILL MEDICAL COLL OF CORNELL UNIV · PI LICHTENTHAL, WENDY G., PRIGERSON, HOLLY GWEN · 2022 to 2025
$3.2M
Pilot Trial of a "Divine Intervention" to Improve End-of-Life Cancer Care for Black PatientsR21MD017652 · NIMHD · WEILL MEDICAL COLL OF CORNELL UNIV · PI MACIEJEWSKI, PAUL K, PRIGERSON, HOLLY GWEN · 2023 to 2025
$495k
The Living Memory Home: Reducing Grief and Improving Relationships between Home-based Patients with ADRD and Their Family CaregiversR21AG077144 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI FALZARANO, FRANCESCA, PRIGERSON, HOLLY GWEN · 2023 to 2024
$481k
Communicating the Gist of Prognosis: An intervention to improve prognostic understanding in advanced lymphomaR21MD017704 · NIMHD · SLOAN-KETTERING INST CAN RESEARCH · PI MCCONNELL, KELLY, PRIGERSON, HOLLY GWEN · 2022 to 2023
$466k
NCI NIH HHS L30 CA294336NCI NIH HHS R01 CA106370NCI NIH HHS R35 CA197730NIA NIH HHS R21 AG077144NIA NIH HHS T32 AG049666NIMHD NIH HHS R21 MD017652NIMHD NIH HHS R21 MD017704NINR NIH HHS R01 NR019831
6 · The paper itself

Abstract

purposeTo determine quality of life (QoL) domains in the months leading up to death associated with the receipt of aggressive care in the last month of life among patients with advanced cancer.

methodsA multisite, prospective cohort study conducted from January 2010 to May 2015 of 59 patients with advanced cancer (distant metastases and/or progression of disease following at least first-line chemotherapy) and poor prognosis (≤ 6 months) followed through death. At baseline, a median of 4 months from death, the McGill Quality of Life Questionnaire measured overall QoL and four QoL domains (i.e., interpersonal support, physical well-being, psychological, and existential). Postmortem data were collected via medical chart review and nurse/caregiver report and combined to capture the aggressiveness of end-of-life (EoL) care in patients' last month of life. Aggressive EoL care was defined as any receipt of care in an intensive care unit, being on a ventilator, or chemotherapy in the last month of life.

resultsPatients with higher interpersonal support domain scores (i.e., rating the world as more "caring and responsive" to their needs and their felt support as more complete) received significantly less aggressive care in their last month of life (odds ratio = 0.39, 95% confidence interval 0.20 to 0.75, p = 0.004).

conclusionPerceived interpersonal support is the only QoL domain assessed that was associated with aggressiveness of care in the last month of life for patients with advanced cancer. Prioritizing caring and responsive relationships for patients may decrease receipt of aggressive EoL care.

Indexed as

NeoplasmsQuality of LifeSocial SupportTerminal CareAdultAgedAged, 80 and overCohort StudiesFemaleHumansMaleMiddle AgedProspective StudiesSurveys and QuestionnairesAdvanced cancerAggressive careEnd of lifeInterpersonal supportQuality of lifeSocial support

Identifiers

PMID39316300
PMCPMC11466437

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.