ArticleEuropean geriatric medicine2024
The role of C-reactive protein as a risk marker of postoperative delirium in older hip fracture patients: a prospective cohort study.
Article in European geriatric medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis for the associations of serum C-reactive protein with delirium risk.Frontiers in neurologyPooled it
- C-reactive protein -albumin-lymphocyte (CALLY) index as a predictor of early mortality in elderly patients with hip fractures.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Article
- Linear association between high-sensitivity C-reactive protein and postoperative delirium after general anesthesia: a cross-sectional study.Frontiers in neurology · 2025Article
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Authors and funding
11 authors.
Funding
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Abstract
purposePostoperative delirium (POD) is a common and serious neuropsychiatric syndrome that leads to higher morbidity and mortality. We investigated the association between serum C-reactive protein (CRP) and the occurrence of POD in older hip fracture patients, and whether CRP predicted POD better than a clinical model.
methodsPatients aged ≥ 75 years admitted for surgical repair of an acute hip fracture were recruited. We compared serum CRP levels between patients with and without POD.
resultsSixty patients were included, of whom 21 (35%) developed POD. Serum CRP levels were significantly higher in patients who developed delirium (p = 0.011). In a multiple regression model including clinical variables and CRP, cognitive impairment (p = 0.003) and infection (p = 0.001) were the best predictors of POD.
conclusionsAlthough higher levels of serum CRP were significantly associated with POD in older hip fracture patients, pre-existing cognitive impairment and infections were the most important risk factors for POD.
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