Evidence map›Paper›PMID 39316262›Full record

ArticleCell biochemistry and biophysics2025

Cinnamaldehyde Alleviates Alveolar Epithelial Cell Injury in ALI by Inhibiting the CaMKII Pathway.

Lei Liu, Hao Zhang, Siming Chen, Wankang Dian, Zhou Zheng

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In one paragraph

Article in Cell biochemistry and biophysics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Lei Liu *Department of Emergency, Wuhan Third Hospital, Tongren Hospital of Wuhan University, Wuhan, China. le110313@163.com.
Hao Zhang *Department of Emergency, Wuhan Third Hospital, Tongren Hospital of Wuhan University, Wuhan, China.
Siming Chen *Department of Emergency, Wuhan Third Hospital, Tongren Hospital of Wuhan University, Wuhan, China.
Wankang Dian *Department of Emergency, Wuhan Third Hospital, Tongren Hospital of Wuhan University, Wuhan, China.
Zhou Zheng *Department of Emergency, Wuhan Third Hospital, Tongren Hospital of Wuhan University, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alveolar epithelial cell injury plays a key role in acute lung injury (ALI) and is a vital determinant of its severity. Here, we aimed to assess the protective effects of cinnamaldehyde (CA) on lipopolysaccharide (LPS)-induced A549 cells and elucidate the underlying mechanisms. A549 cells were stimulated with 1 μg/mL LPS for 24 h to establish an alveolar epithelial cell injury model and subsequently treated with CA or Ca

Indexed as

AcroleinAcute Lung InjuryAlveolar Epithelial CellsCalcium-Calmodulin-Dependent Protein Kinase Type 2Signal TransductionA549 CellsApoptosisBenzenesulfonamidesBenzylaminesCell SurvivalCytokinesHumansLipopolysaccharidesOxidative StressReactive Oxygen SpeciesSulfonamidesAcroleinBenzenesulfonamidesBenzylaminesCalcium-Calmodulin-Dependent Protein Kinase Type 2cinnamaldehydeCytokinesKN 93LipopolysaccharidesReactive Oxygen SpeciesSulfonamidesAcute lung injuryCaMKII pathwayCinnamaldehyde

Identifiers

PMID39316262

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.