Evidence map›Paper›PMID 39316251›Full record

ArticleCellular oncology (Dordrecht, Netherlands)2024

Clinical value of

Jiamin Fang, Jie Chen, Xinqi Li, Pengpeng Li, Xiaoyan Liu, Yong He, Fuling Zhou

Abstract read
In one paragraph

Article in Cellular oncology (Dordrecht, Netherlands), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Baseline [European journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiamin FangDepartment of Hematology, Zhongnan Hospital of Wuhan University, No.169 Donghu Road, Wuhan, 430071, China.
Jie ChenDepartment of Nuclear Medicine, Zhongnan Hospital of Wuhan University, No.169 Donghu Road, Wuhan, 430071, China.
Xinqi LiDepartment of Hematology, Zhongnan Hospital of Wuhan University, No.169 Donghu Road, Wuhan, 430071, China.
Pengpeng LiDepartment of Hematology, Zhongnan Hospital of Wuhan University, No.169 Donghu Road, Wuhan, 430071, China.
Xiaoyan LiuDepartment of Hematology, Zhongnan Hospital of Wuhan University, No.169 Donghu Road, Wuhan, 430071, China. liuxiaoyan@znhospital.cn.
Yong HeDepartment of Nuclear Medicine, Zhongnan Hospital of Wuhan University, No.169 Donghu Road, Wuhan, 430071, China. vincentheyong@163.com.
Fuling ZhouDepartment of Hematology, Zhongnan Hospital of Wuhan University, No.169 Donghu Road, Wuhan, 430071, China. zhoufuling@whu.edu.cn.

Funding

National Natural Science Foundation of China 81900116, 82370176, 82000127, 82200254Zhongnan Hospital of Wuhan University discipline construction plat form project 202021, PDJH202217
6 · The paper itself

Abstract

purposeTo explore the correlation between semi-quantitative parameters of

methodsA retrospective study was conducted with 44 patients newly diagnosed with acute leukemia (AL) at Zhongnan Hospital of Wuhan University between January 2019 and August 2024.

resultsMultivariate analysis revealed that age at diagnosis of AL (odds ratio [OR]: 0.888, P < 0.01) and percentage of blasts in the peripheral blood (PB) (OR: 1.061, P < 0.05) were independent predictors of the appearance of active extramedullary disease (EMD). Kaplan-Meier survival analysis for patients with EMD(+) indicated that those with organ infiltration beyond the lymph nodes experienced markedly reduced overall survival (OS) compared to those without such infiltration (157 days and 806 days, respectively). Furthermore, in the AL subgroup with EMD, the ratio of the maximum standardized uptake value (SUVmax) in the bone marrow (BM) to SUVmax of the liver emerged as an independent prognostic factor for OS (Hazard ratio [HR]: 2.372; 95% confidence interval [CI]: 1.079-5.214, P < 0.05).

conclusion

Indexed as

Fluorodeoxyglucose F18Positron Emission Tomography Computed TomographyAcute DiseaseAdolescentAdultAgedFemaleHumansKaplan-Meier EstimateLeukemiaMaleMiddle AgedPrognosisRetrospective StudiesYoung AdultFluorodeoxyglucose F18Acute leukemiaExtramedullary diseaseMetabolic parametersPET/CT

Identifiers

PMID39316251
PMCPMC12974071

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.