Evidence map›Paper›PMID 39316117›Full record

SynthesisClinical neuroradiology2024

Comprehensive Evaluation of Serpentine Aneurysms: a Systematic Review and Meta-analysis with a Subanalysis for Treatment Approaches.

Celal Cinar, Alperen Elek, Irshad Allahverdiyev, Kenan Kerem Ozcinar, Adem C Yazici, Mahmut Kusbeci, Egemen Ozturk, Ismail Oran

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Clinical neuroradiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Short to mid-term outcomes of flow re-direction endoluminal device X (FREDDiagnostic and interventional radiology (Ankara, Turkey) · 2026
    Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Celal CinarDepartment of Interventional Radiology, Faculty of Medicine, Ege University, 35100, Izmir, Turkey.
Alperen ElekDepartment of Interventional Radiology, Faculty of Medicine, Ege University, 35100, Izmir, Turkey. alperenelek13@gmail.com.ORCID http://orcid.org/0000-0001-5414-6548
Irshad AllahverdiyevFaculty of Medicine, Istanbul University, Istanbul, Turkey.
Kenan Kerem OzcinarFaculty of Medicine, Bahcesehir University, Istanbul, Turkey.
Adem C YaziciFaculty of Medicine, Bahcesehir University, Istanbul, Turkey.
Mahmut KusbeciDepartment of Interventional Radiology, Faculty of Medicine, Ege University, 35100, Izmir, Turkey.
Egemen OzturkDepartment of Radiology, Usak Training and Research Hospital, Usak, Turkey.
Ismail OranDepartment of Interventional Radiology, Faculty of Medicine, Ege University, 35100, Izmir, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis systematic review and meta-analysis aimed to systematically evaluate and enhance the understanding of optimal management strategies for serpentine aneurysms.

methodsA systematic search was conducted in Medline, Scopus, and Cochrane databases up to July 8, 2024, using relevant keywords. Studies included were case series, prospective or retrospective cohorts, or randomized controlled trials with data on clinical and angiographic outcomes of intracranial serpentine aneurysms. Data extraction and quality assessment were performed independently by two authors. Statistical analysis was conducted using R, with pooled estimates under a random-effects model.

resultsTen studies comprising 70 patients with 71 serpentine aneurysms were included. The majority (92.9%) were giant aneurysms. The overall rate of procedure-related complications was 33%, morbidity was 13%, and mortality was 13%. Good neurological outcomes were achieved in 76% of cases. For unruptured aneurysms, the complication rate was 34%, while no complications were observed in ruptured aneurysms. Comparative analysis between ruptured and unruptured aneurysms showed no significant differences in outcomes or complications. The technical success rate was 91%. Reconstructive methods showed a slightly higher rate of good neurological outcomes (77%) compared to deconstructive methods (70%), though complication rates were similar.

conclusionBoth reconstructive and deconstructive endovascular treatments for serpentine aneurysms are effective, with high rates of good neurological outcomes and acceptable complication rates.

Indexed as

Endovascular ProceduresIntracranial AneurysmAneurysm, RupturedEmbolization, TherapeuticHumansPostoperative ComplicationsTreatment OutcomeClinical outcomeComplicationDeconstructive approachGiant serpentine aneurysmReconstructive approachSerpentine aneurysm

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.