ArticleProceedings of the National Academy of Sciences of the United States of America2024
Repetition dynamically and rapidly increases cortical, but not hippocampal, offline reactivation.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Increased corticospinal excitability after rest with short term motor performance.Experimental physiology · 2026Article
- A large-scale heterogeneous 3D magnetic resonance brain imaging dataset for self-supervised learning.Scientific data · 2026Article
- The default mode network: where spontaneous thought meets memory consolidation.Current opinion in behavioral sciences · 2026Article
- The mentalizing network updates neural representations of romantic interest in response to social feedback.Social cognitive and affective neuroscience · 2026Article
- Article
- Resting after learning or repeating the learned?Psychonomic bulletin & review · 2025Article
- The Default Network and Social Cognition: New Insights and Future Directions.Current opinion in behavioral sciences · 2025Article
- Rich autobiographical memory benefits from both novelty and similarity to other daily experiences.Scientific reports · 2025Article
- Spontaneous reinstatement of episodic memories in the developing human brain.bioRxiv : the preprint server for biology · 2025Article
- Rich autobiographical memory recall benefits from both novelty and similarity to other daily experiences.Research square · 2025Article
- Replay in the human visual cortex during brief task pauses is linked to implicit learning of successor representations.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Positive Emotion Enhances Memory by Promoting Memory Reinstatement across Repeated Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Reactivation and consolidation of memory traces during post-encoding rest across the adult lifespan.Annals of clinical and translational neurology · 2025Review
- Repetition dynamically and rapidly increases cortical, but not hippocampal, offline reactivation.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
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4 authors.
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Abstract
No sooner is an experience over than its neural representation begins to be transformed through memory reactivation during offline periods. The lion's share of prior research has focused on understanding offline reactivation within the hippocampus. However, it is hypothesized that consolidation processes involve offline reactivation in cortical regions as well as coordinated reactivation in the hippocampus and cortex. Using fMRI, we presented novel and repeated paired associates to participants during encoding and measured offline memory reactivation for those events during an immediate post-encoding rest period. post-encoding reactivation frequency of repeated and once-presented events did not differ in the hippocampus. However, offline reactivation in widespread cortical regions and hippocampal-cortical coordinated reactivation were significantly enhanced for repeated events. These results provide evidence that repetition might facilitate the distribution of memory representations across cortical networks, a hallmark of systems-level consolidation. Interestingly, we found that offline reactivation frequency in both hippocampus and cortex explained variance in behavioral success on an immediate associative recognition test for the once-presented information, potentially indicating a role of offline reactivation in maintaining these novel, weaker, memories. Together, our findings highlight that endogenous offline reactivation can be robustly and significantly modulated by study repetition.
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